{"id":442254,"date":"2022-11-28T13:25:38","date_gmt":"2022-11-28T10:25:38","guid":{"rendered":"https:\/\/kinsta.unitedwithisrael.org\/?p=442254"},"modified":"2022-11-29T11:45:53","modified_gmt":"2022-11-29T08:45:53","slug":"une-nouvelle-technologie-israelienne-permet-dextraire-des-tumeurs-sans-chirurgies","status":"publish","type":"post","link":"https:\/\/kinsta.unitedwithisrael.org\/fr\/une-nouvelle-technologie-israelienne-permet-dextraire-des-tumeurs-sans-chirurgies\/","title":{"rendered":"Une nouvelle technologie isra\u00e9lienne permet d’extraire des tumeurs sans chirurgies"},"content":{"rendered":"

Une combinaison d’ultrasons et de nanobulles permet de d\u00e9truire les tumeurs canc\u00e9reuses, \u00e9liminant ainsi le besoin de traitements invasifs.<\/strong><\/em><\/p>\n

(D\u00e9claration du porte-parole de l’Universit\u00e9 de Tel Aviv)<\/em><\/p>\n

Une nouvelle technologie d\u00e9velopp\u00e9e \u00e0 l’Universit\u00e9 de Tel-Aviv permet de d\u00e9truire s\u00e9lectivement les tumeurs canc\u00e9reuses gr\u00e2ce \u00e0 une combinaison d’ultrasons et d’injection de nanobulles dans la circulation sanguine. Selon l’\u00e9quipe de recherche, contrairement aux m\u00e9thodes de traitement invasives ou \u00e0 l’injection de microbulles dans la tumeur elle-m\u00eame, cette derni\u00e8re technologie permet la destruction de la tumeur de mani\u00e8re non invasive.<\/p>\n

L’\u00e9tude a \u00e9t\u00e9 men\u00e9e sous la direction du doctorant Mik Bismuth du laboratoire du Dr Tali Ilovitsh du D\u00e9partement de g\u00e9nie biom\u00e9dical de l’Universit\u00e9 de Tel Aviv, en collaboration avec le Dr Dov Hershkovitz du D\u00e9partement de pathologie. Le professeur Agata Exner, de la Case Western Reserve University de Cleveland, a \u00e9galement particip\u00e9 \u00e0 l’\u00e9tude. L’\u00e9tude a \u00e9t\u00e9 publi\u00e9e dans la revue Nanoscale.<\/p>\n

Le Dr Tali Ilovitsh, note : \u00ab Notre nouvelle technologie permet, de mani\u00e8re relativement simple, d’injecter des nanobulles dans le sang, qui se concentrent ensuite dans la zone de la tumeur canc\u00e9reuse. Apr\u00e8s cela, \u00e0 l’aide d’ultrasons \u00e0 basse fr\u00e9quence, nous avons fait exploser les nanobulles et donc la tumeur<\/em> \u00bb.<\/p>\n

Les chercheurs expliquent qu’actuellement, la m\u00e9thode pr\u00e9dominante de traitement du cancer est l’ablation chirurgicale de la tumeur, en combinaison avec des traitements compl\u00e9mentaires tels que la chimioth\u00e9rapie et l’immunoth\u00e9rapie. L’\u00e9chographie th\u00e9rapeutique pour d\u00e9truire la tumeur canc\u00e9reuse est une alternative non invasive \u00e0 la chirurgie.<\/p>\n

Cette m\u00e9thode pr\u00e9sente \u00e0 la fois des avantages et des inconv\u00e9nients. D’une part, elle permet un traitement localis\u00e9 et focalis\u00e9 ; l’utilisation d’ultrasons de haute intensit\u00e9 peut produire des effets thermiques ou m\u00e9caniques en d\u00e9livrant une puissante \u00e9nergie acoustique en un point central avec une grande pr\u00e9cision spatio-temporelle. Cette m\u00e9thode a \u00e9t\u00e9 utilis\u00e9e pour le traitement efficace des tumeurs solides dans le corps. De plus, elle permet de traiter des patients qui ne se pr\u00eatent pas \u00e0 une chirurgie de r\u00e9section tumorale. L’inconv\u00e9nient, cependant, est que la chaleur et la haute intensit\u00e9 des ondes ultrasonores peuvent endommager les tissus proches de la tumeur.<\/p>\n

Dans la pr\u00e9sente \u00e9tude, le Dr Ilovitsh et son \u00e9quipe ont tent\u00e9 de surmonter ce probl\u00e8me. Dans l’exp\u00e9rience, o\u00f9 ils ont utilis\u00e9 un mod\u00e8le animal, les chercheurs ont pu d\u00e9truire la tumeur en injectant des nanobulles dans la circulation sanguine (contrairement \u00e0 ce qui avait \u00e9t\u00e9 utilis\u00e9 jusqu’\u00e0 pr\u00e9sent, qui \u00e9tait l’injection locale de microbulles dans la tumeur elle-m\u00eame), en combinaison avec des ondes ultrasonores \u00e0 basse fr\u00e9quence, avec un minimum d’effets ind\u00e9sirables.<\/p>\n

Le Dr Ilovitsh d\u00e9clare : \u00ab La combinaison de nanobulles et d’ondes ultrasonores \u00e0 basse fr\u00e9quence permet un ciblage plus sp\u00e9cifique de la zone tumorale et r\u00e9duit la toxicit\u00e9 ind\u00e9sirable. L’application de basse fr\u00e9quence aux nanobulles g\u00e9n\u00e8re leur gonflement extr\u00eame et leur explosion, m\u00eame \u00e0 basse pression. Cela permet de r\u00e9aliser la destruction m\u00e9canique des tumeurs \u00e0 des seuils de pression faibles. Notre m\u00e9thode pr\u00e9sente les avantages de l’\u00e9chographie, en ce sens qu’elle est s\u00fbre, rentable et cliniquement disponible, et en plus, l’utilisation de nanobulles facilite la localisation des tumeurs car elles peuvent \u00eatre observ\u00e9es \u00e0 l’aide d’images \u00e9chographiques.<\/em>\u00a0\u00bb<\/p>\n

Le Dr Ilovitsh ajoute que l’utilisation d’ultrasons \u00e0 basse fr\u00e9quence augmente \u00e9galement la profondeur de p\u00e9n\u00e9tration, minimise la distorsion et l’att\u00e9nuation et \u00e9largit le point focal. \u00ab\u00a0Cela peut aider au traitement des tumeurs situ\u00e9es profond\u00e9ment dans le corps et \u00e9galement faciliter le traitement des tumeurs d’un volume plus important. L’exp\u00e9rience a \u00e9t\u00e9 r\u00e9alis\u00e9e sur un mod\u00e8le de souris avec une tumeur canc\u00e9reuse du sein, mais il est probable que le traitement sera \u00e9galement efficace avec d’autres types de tumeurs, et \u00e0 l’avenir, \u00e9galement chez l’homme.<\/em>\u00a0\u00bb<\/p>\n

Keren Primor Cohen, directrice g\u00e9n\u00e9rale de Ramot, note : \u00ab La soci\u00e9t\u00e9 de transfert de technologie Ramot, de l’universit\u00e9 de Tel Aviv, a d\u00e9pos\u00e9 plusieurs brevets pour prot\u00e9ger cette technologie et son application. Nous croyons au potentiel commercial de cette technologie innovante dans le traitement du cancer et sommes en contact avec diverses soci\u00e9t\u00e9s leaders en Isra\u00ebl et \u00e0 l’\u00e9tranger afin de la promouvoir<\/em>.\u00a0\u00bb<\/p>\n

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Une combinaison d’ultrasons et de nanobulles permet de d\u00e9truire les tumeurs canc\u00e9reuses, \u00e9liminant ainsi le besoin de traitements invasifs. (D\u00e9claration du porte-parole de l’Universit\u00e9 de Tel Aviv) Une nouvelle technologie d\u00e9velopp\u00e9e \u00e0 l’Universit\u00e9 de Tel-Aviv permet de d\u00e9truire s\u00e9lectivement les tumeurs canc\u00e9reuses gr\u00e2ce \u00e0 une combinaison d’ultrasons et d’injection de nanobulles dans la circulation sanguine…. Read more »<\/a><\/p>\n","protected":false},"author":4242,"featured_media":298492,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[28414],"tags":[34248,29798,29313,29783,28445],"class_list":["post-442254","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-influence-israelienne","tag-innovation-fr","tag-medecine","tag-recherche","tag-sante","tag-technologie"],"better_featured_image":{"id":298492,"alt_text":"A researcher at the Technion Israel Institute of Technology in Haifa (Hadas Parush\/Flash90)","caption":"A researcher at the Technion Israel Institute of Technology in Haifa (Hadas Parush\/Flash90)","description":"Pesquisador no Instituto Technion na cidade de Haifa 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