{"id":401035,"date":"2021-09-14T15:34:31","date_gmt":"2021-09-14T12:34:31","guid":{"rendered":"https:\/\/kinsta.unitedwithisrael.org\/?p=401035"},"modified":"2021-09-14T14:32:25","modified_gmt":"2021-09-14T11:32:25","slug":"decouverte-israelienne-certains-globules-blancs-permettent-de-lutter-contre-le-cancer","status":"publish","type":"post","link":"https:\/\/kinsta.unitedwithisrael.org\/fr\/decouverte-israelienne-certains-globules-blancs-permettent-de-lutter-contre-le-cancer\/","title":{"rendered":"D\u00e9couverte isra\u00e9lienne: certains globules blancs permettent de lutter contre le cancer"},"content":{"rendered":"

Les d\u00e9couvertes de l’Universit\u00e9 de Tel Aviv ouvrent de nouvelles possibilit\u00e9s en mati\u00e8re de d\u00e9veloppement de traitements contre le cancer.<\/strong><\/em><\/p>\n

Par Pesach Benson, Unis avec Isra\u00ebl<\/em><\/p>\n

Des chercheurs de l’Universit\u00e9 de Tel Aviv ont d\u00e9couvert qu’un certain type de globule blanc pouvait \u00eatre utilis\u00e9 pour lutter contre le cancer, ouvrant de nouvelles possibilit\u00e9s pour le d\u00e9veloppement de traitements contre le cancer.<\/p>\n

Le professeur Ariel Munitz et la doctorante Sharon Grisauri du d\u00e9partement de microbiologie et d’immunologie clinique de la facult\u00e9 de m\u00e9decine Sackler ont dirig\u00e9 la recherche. Les r\u00e9sultats ont \u00e9t\u00e9 publi\u00e9s dans Cancer Research, une importante revue de l’American Association for Cancer Research.<\/p>\n

L’\u00e9tude s’est concentr\u00e9e sur les \u00e9osinophiles – un type de globule blanc. Ils produisent leurs propres prot\u00e9ines destructrices, tout en invoquant les cellules T du syst\u00e8me immunitaire qui combattent le cancer. Selon les chercheurs, les prot\u00e9ines produites par les \u00e9osinophiles \u00e9taient \u00e0 l’origine destin\u00e9es \u00e0 lutter contre les parasites. Mais les \u00e9osinophiles peuvent \u00e9galement avoir un effet n\u00e9gatif sur le corps humain en induisant des allergies ou de l’asthme.<\/p>\n

Le Dr Munitz a \u00e9mis l’hypoth\u00e8se que le pouvoir destructeur des prot\u00e9ines des \u00e9osinophiles pourrait \u00eatre exploit\u00e9 pour combattre les cellules canc\u00e9reuses.<\/p>\n

Les chercheurs ont commenc\u00e9 par examiner des tissus canc\u00e9reux humains – des biopsies de m\u00e9tastases pulmonaires pr\u00e9lev\u00e9es sur des patientes atteintes d’un cancer du sein. Ils ont d\u00e9couvert que les \u00e9osinophiles atteignent les poumons et p\u00e9n\u00e8trent dans les tissus canc\u00e9reux, o\u00f9 ils lib\u00e8rent souvent les prot\u00e9ines destructrices qu’ils transportent.<\/p>\n

L’\u00e9quipe de l’universit\u00e9 de Tel Aviv a ensuite test\u00e9 les \u00e9osinphiles sur des souris. Apr\u00e8s neuf jours, les chercheurs ont d\u00e9couvert que les tumeurs des souris auxquelles des \u00e9osinophiles avaient \u00e9t\u00e9 inject\u00e9s avaient en moyenne la moiti\u00e9 de la taille des tumeurs des souris qui n’avaient re\u00e7u aucune injection.<\/p>\n

Ils ont \u00e9galement d\u00e9couvert qu’en pr\u00e9sence d’un cancer, les \u00e9osinophiles lib\u00e8rent de grandes quantit\u00e9s de chimiokines – des substances qui invoquent les cellules T du corps. L’arriv\u00e9e de cellules T suppl\u00e9mentaires renforce la lutte de l’organisme contre le cancer, ralentissant consid\u00e9rablement la croissance de la tumeur.<\/p>\n

\u00ab\u00a0En fin de compte, notre \u00e9tude pourrait servir de base au d\u00e9veloppement de m\u00e9dicaments immunoth\u00e9rapeutiques am\u00e9lior\u00e9s qui emploient des \u00e9osinophiles pour combattre le cancer de deux mani\u00e8res<\/em>\u00ab\u00a0, a d\u00e9clar\u00e9 le Dr Munitz. \u00ab\u00a0D’une part, les \u00e9osinophiles attaqueront directement le cancer en lib\u00e9rant leurs propres prot\u00e9ines destructrices, tandis que d’autre part, ils augmenteront le nombre de cellules T dans l’environnement du cancer. Nous pensons que l’effet combin\u00e9 peut am\u00e9liorer consid\u00e9rablement l’efficacit\u00e9 du traitement.\u00a0\u00bb<\/em><\/p>\n

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Les d\u00e9couvertes de l’Universit\u00e9 de Tel Aviv ouvrent de nouvelles possibilit\u00e9s en mati\u00e8re de d\u00e9veloppement de traitements contre le cancer. Par Pesach Benson, Unis avec Isra\u00ebl Des chercheurs de l’Universit\u00e9 de Tel Aviv ont d\u00e9couvert qu’un certain type de globule blanc pouvait \u00eatre utilis\u00e9 pour lutter contre le cancer, ouvrant de nouvelles possibilit\u00e9s pour le… Read more »<\/a><\/p>\n","protected":false},"author":4242,"featured_media":380477,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[28418],"tags":[33896,34248,29798,29313,29783],"class_list":["post-401035","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-actualites-israeliennes","tag-cancer-fr","tag-innovation-fr","tag-medecine","tag-recherche","tag-sante"],"better_featured_image":{"id":380477,"alt_text":"","caption":"Shutterstock","description":"","media_type":"image","media_details":{"width":2560,"height":1709,"file":"2021\/02\/shutterstock_751727689-scaled.jpg","sizes":{"medium":{"file":"shutterstock_751727689-300x200.jpg","width":300,"height":200,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_751727689-300x200.jpg"},"large":{"file":"shutterstock_751727689-1024x683.jpg","width":1024,"height":683,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_751727689-1024x683.jpg"},"thumbnail":{"file":"shutterstock_751727689-150x150.jpg","width":150,"height":150,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_751727689-150x150.jpg"},"medium_large":{"file":"shutterstock_751727689-768x513.jpg","width":768,"height":513,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_751727689-768x513.jpg"},"1536x1536":{"file":"shutterstock_751727689-1536x1025.jpg","width":1536,"height":1025,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_751727689-1536x1025.jpg"},"uwi-full-width":{"file":"shutterstock_751727689-780x520.jpg","width":780,"height":520,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_751727689-780x520.jpg"},"uwi-featured-carousel":{"file":"shutterstock_751727689-890x400.jpg","width":890,"height":400,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_751727689-890x400.jpg"},"uwi-featured-content":{"file":"shutterstock_751727689-290x160.jpg","width":290,"height":160,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_751727689-290x160.jpg"},"uwi-content-loop":{"file":"shutterstock_751727689-190x190.jpg","width":190,"height":190,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_751727689-190x190.jpg"},"uwi-category_list":{"file":"shutterstock_751727689-180x100.jpg","width":180,"height":100,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_751727689-180x100.jpg"},"uwi-tiny":{"file":"shutterstock_751727689-40x40.jpg","width":40,"height":40,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_751727689-40x40.jpg"},"uwi-email-featured":{"file":"shutterstock_751727689-250x170.jpg","width":250,"height":170,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_751727689-250x170.jpg"},"uwi-email":{"file":"shutterstock_751727689-200x140.jpg","width":200,"height":140,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_751727689-200x140.jpg"},"uwi-iphone":{"file":"shutterstock_751727689-960x640.jpg","width":960,"height":640,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_751727689-960x640.jpg"},"uwi-iphone-x2":{"file":"shutterstock_751727689-1136x640.jpg","width":1136,"height":640,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_751727689-1136x640.jpg"},"uwi-ipad":{"file":"shutterstock_751727689-1024x768.jpg","width":1024,"height":768,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_751727689-1024x768.jpg"},"uwi-full-width-video":{"file":"shutterstock_751727689-779x519.jpg","width":779,"height":519,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_751727689-779x519.jpg"},"uwi-fb-share-video":{"file":"shutterstock_751727689-600x315.jpg","width":600,"height":315,"mime-type":"image\/jpeg","source_url":"https:\/\/ki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