{"id":390565,"date":"2021-11-15T08:19:07","date_gmt":"2021-11-15T05:19:07","guid":{"rendered":"https:\/\/kinsta.unitedwithisrael.org\/?p=390565"},"modified":"2021-06-01T16:16:42","modified_gmt":"2021-06-01T13:16:42","slug":"decouverte-israelienne-cette-proteine-qui-rallonge-la-duree-de-vie-de-30","status":"publish","type":"post","link":"https:\/\/kinsta.unitedwithisrael.org\/fr\/decouverte-israelienne-cette-proteine-qui-rallonge-la-duree-de-vie-de-30\/","title":{"rendered":"D\u00e9couverte isra\u00e9lienne: cette prot\u00e9ine qui rallonge la dur\u00e9e de vie de 30%"},"content":{"rendered":"

\u00ab\u00a0Si nous pouvons d\u00e9terminer comment activer [cette prot\u00e9ine] chez l’homme, nous pourrons prolonger la vie\u00a0\u00bb, a d\u00e9clar\u00e9 le professeur Haim Cohen.<\/strong><\/em><\/p>\n

Par Abigail Klein Leichman, Isra\u00ebl21c<\/em><\/p>\n

L’esp\u00e9rance de vie a augment\u00e9 de 30% en moyenne chez les souris m\u00e2les et femelles programm\u00e9es pour pr\u00e9senter des niveaux \u00e9lev\u00e9s d’une prot\u00e9ine appel\u00e9e SIRT6, a rapport\u00e9 une \u00e9quipe de scientifiques internationaux dans la revue Nature Communications.<\/p>\n

Les souris \u00e9taient \u00e9galement mieux \u00e0 m\u00eame de surmonter les maladies li\u00e9es \u00e0 l’\u00e2ge telles que le cancer et les troubles sanguins, et sont rest\u00e9es vigoureuses en vieillissant plut\u00f4t que de devenir fragiles.<\/p>\n

L’\u00e9tude a \u00e9t\u00e9 dirig\u00e9e par le professeur Haim Cohen, directeur du Sagol Healthy Human Longevity Center de l’Universit\u00e9 Bar-Ilan en Isra\u00ebl. Les recherches de Cohen se concentrent depuis longtemps sur la fa\u00e7on dont SIRT6 est impliqu\u00e9e dans la r\u00e9gulation des processus biologiques tels que le vieillissement, l’ob\u00e9sit\u00e9 et la r\u00e9sistance \u00e0 l’insuline.<\/p>\n

L’\u00e9quipe a utilis\u00e9 des m\u00e9thodes biochimiques et des analyses m\u00e9taboliques pour d\u00e9couvrir le m\u00e9canisme par lequel SIRT6 agit comme une sorte de \u00ab\u00a0fontaine de jouvence\u00a0<\/em>\u00bb.<\/p>\n

Alors que les animaux plus \u00e2g\u00e9s subissent g\u00e9n\u00e9ralement une baisse d’\u00e9nergie, le corps des souris avec SIRT6 suppl\u00e9mentaire a d\u00e9compos\u00e9 les graisses et l’acide lactique pour cr\u00e9er du sucre utilis\u00e9 pour l’\u00e9nergie dans leurs muscles et leur cerveau.<\/p>\n

\u00ab\u00a0Cette d\u00e9couverte, combin\u00e9e \u00e0 nos r\u00e9sultats pr\u00e9c\u00e9dents, montre que SIRT6 contr\u00f4le le taux de vieillissement en bonne sant\u00e9\u00a0\u00bb,<\/em> a d\u00e9clar\u00e9 Cohen.<\/p>\n

\u00ab\u00a0Si nous pouvons d\u00e9terminer comment l’activer chez l’homme, nous pourrons prolonger la vie, et cela pourrait avoir d’\u00e9normes implications sanitaires et \u00e9conomiques.\u00a0\u00bb<\/em><\/p>\n

Cohen a r\u00e9alis\u00e9 l’\u00e9tude avec son doctorant Asael Roichman ; le professeur Eyal Gottlieb du Technion-Israel Institute of Technology; le professeur Rafael de Cabo du National Institute on Aging des National Institutes of Health des \u00c9tats-Unis; et le professeur Manuel Serrani de l’Institut de recherche en biom\u00e9decine de Barcelone.<\/p>\n

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\u00ab\u00a0Si nous pouvons d\u00e9terminer comment activer [cette prot\u00e9ine] chez l’homme, nous pourrons prolonger la vie\u00a0\u00bb, a d\u00e9clar\u00e9 le professeur Haim Cohen. Par Abigail Klein Leichman, Isra\u00ebl21c L’esp\u00e9rance de vie a augment\u00e9 de 30% en moyenne chez les souris m\u00e2les et femelles programm\u00e9es pour pr\u00e9senter des niveaux \u00e9lev\u00e9s d’une prot\u00e9ine appel\u00e9e SIRT6, a rapport\u00e9 une \u00e9quipe… Read more »<\/a><\/p>\n","protected":false},"author":4242,"featured_media":380477,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[28414],"tags":[34044,28711,34248,29313,29783],"class_list":["post-390565","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-influence-israelienne","tag-decouverte","tag-esperance-de-vie","tag-innovation-fr","tag-recherche","tag-sante"],"better_featured_image":{"id":380477,"alt_text":"","caption":"Shutterstock","description":"","media_type":"image","media_details":{"width":2560,"height":1709,"file":"2021\/02\/shutterstock_751727689-scaled.jpg","sizes":{"medium":{"file":"shutterstock_751727689-300x200.jpg","width":300,"height":200,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_751727689-300x200.jpg"},"large":{"file":"shutterstock_751727689-1024x683.jpg","width":1024,"height":683,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_751727689-1024x683.jpg"},"thumbnail":{"file":"shutterstock_751727689-150x150.jpg","width":150,"height":150,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_751727689-150x150.jpg"},"medium_large":{"file":"shutterstock_751727689-768x513.jpg","width":768,"height":513,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_751727689-768x513.jpg"},"1536x1536":{"file":"shutterstock_751727689-1536x1025.jpg","width":1536,"height":1025,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_751727689-1536x1025.jpg"},"uwi-full-width":{"file":"shutterstock_751727689-780x520.jpg","width":780,"height":520,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_751727689-780x520.jpg"},"uwi-featured-carousel":{"file":"shutterstock_751727689-890x400.jpg","width":890,"height":400,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_751727689-890x400.jpg"},"uwi-featured-content":{"file":"shutterstock_751727689-290x160.jpg","width":290,"height":160,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_751727689-290x160.jpg"},"uwi-content-loop":{"file":"shutterstock_751727689-190x190.jpg","width":190,"height":190,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_751727689-190x190.jpg"},"uwi-category_list":{"file":"shutterstock_751727689-180x100.jpg","width":180,"height":100,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_751727689-180x100.jpg"},"uwi-tiny":{"file":"shutterstock_751727689-40x40.jpg","width":40,"height":40,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_751727689-40x40.jpg"},"uwi-email-featured":{"file":"shutterstock_751727689-250x170.jpg","width":250,"height":170,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_751727689-250x170.jpg"},"uwi-email":{"file":"shutterstock_751727689-200x140.jpg","width":200,"height":140,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_751727689-200x140.jpg"},"uwi-iphone":{"file":"shutterstock_751727689-960x640.jpg","width":960,"height":640,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_751727689-960x640.jpg"},"uwi-iphone-x2":{"file":"shutterstock_751727689-1136x640.jpg","width":1136,"height":640,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_751727689-1136x640.jpg"},"uwi-ipad":{"file":"shutterstock_751727689-1024x768.jpg","width":1024,"height":768,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_751727689-1024x768.jpg"},"uwi-full-width-video":{"file":"shutterstock_751727689-779x519.jpg","width":779,"height":519,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_751727689-779x519.jpg"},"uwi-fb-share-video":{"file":"shutterstock_751727689-600x315.jpg","width":600,"height":315,"mime-type":"image\/jpeg","source_url":"https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