{"id":378886,"date":"2021-02-09T15:50:16","date_gmt":"2021-02-09T12:50:16","guid":{"rendered":"https:\/\/kinsta.unitedwithisrael.org\/?p=378886"},"modified":"2021-02-10T12:20:53","modified_gmt":"2021-02-10T09:20:53","slug":"detecter-le-cancer-par-simple-prise-de-sang-la-nouvelle-percee-israelienne","status":"publish","type":"post","link":"https:\/\/kinsta.unitedwithisrael.org\/fr\/detecter-le-cancer-par-simple-prise-de-sang-la-nouvelle-percee-israelienne\/","title":{"rendered":"D\u00e9tecter le cancer par simple prise de sang, la nouvelle perc\u00e9e isra\u00e9lienne"},"content":{"rendered":"

Des chercheurs de l’Universit\u00e9 h\u00e9bra\u00efque ont mis au point un nouveau test sanguin susceptible de diagnostiquer un large \u00e9ventail de maladies.<\/strong><\/em><\/p>\n

Par Yakir Benzion, Unis avec Isra\u00ebl<\/em><\/p>\n

\u00catre gravement malade n’est jamais amusant et souvent tr\u00e8s compliqu\u00e9 lorsque des examens invasifs sont n\u00e9cessaires, mais une \u00e9quipe de recherche isra\u00e9lienne a d\u00e9velopp\u00e9 un nouveau test sanguin qui a le potentiel de diagnostiquer un large \u00e9ventail de maladies – y compris les cancers, les maladies du foie, les troubles immunitaires et d’autres maladies – sans avoir besoin de biopsies douloureuses et parfois dangereuses.<\/p>\n

En utilisant des techniques avanc\u00e9es qui suivent l’ADN de diff\u00e9rentes parties du corps, le test s’est av\u00e9r\u00e9 extr\u00eamement pr\u00e9cis avec la possibilit\u00e9 de rendre compte de l’\u00e9tat exact et de l’emplacement de la maladie dans le corps.<\/p>\n

\u00ab\u00a0En m\u00e9decine diagnostique, les biopsies, o\u00f9 un \u00e9chantillon de tissu est extrait pour analyse, sont des outils courants pour la d\u00e9tection de nombreuses conditions<\/em>\u00ab\u00a0, a indiqu\u00e9 le communiqu\u00e9 de l’Universit\u00e9 h\u00e9bra\u00efque de J\u00e9rusalem. \u00ab\u00a0Mais cette approche pr\u00e9sente plusieurs inconv\u00e9nients – elle peut \u00eatre douloureuse, n’extrait pas toujours le tissu malade et ne peut \u00eatre utilis\u00e9e qu’\u00e0 un stade de la maladie suffisamment avanc\u00e9, ce fait qu’il est, dans certains cas, trop tard pour une intervention. Ces pr\u00e9occupations ont encourag\u00e9 chercheurs pour trouver des options moins invasives et plus pr\u00e9cises pour les diagnostics.<\/em> \u00a0\u00bb<\/p>\n

Le professeur Nir Friedman et le Dr Ronen Sadeh ont dirig\u00e9 une \u00e9quipe de 31 chercheurs qui ont r\u00e9cemment publi\u00e9 leurs r\u00e9sultats dans la revue scientifique Nature Biotechnology, qui montre comment un large \u00e9ventail de maladies peut \u00eatre d\u00e9tect\u00e9 par un simple test sanguin.<\/p>\n

Le test permet aux techniciens de laboratoire d’identifier et de d\u00e9terminer l’\u00e9tat des cellules mortes dans tout le corps et ainsi de diagnostiquer diverses maladies, y compris les cancers et les maladies du c\u0153ur et du foie. Le test est m\u00eame capable d’identifier des marqueurs sp\u00e9cifiques qui peuvent diff\u00e9rer entre les patients souffrant des m\u00eames types de croissance tumorale, une caract\u00e9ristique qui a le potentiel d’aider les m\u00e9decins \u00e0 d\u00e9velopper des traitements personnalis\u00e9s pour des patients individuels.<\/p>\n

Comment l’ont-ils fait? Dans le cadre du processus naturel \u00e0 l’int\u00e9rieur de notre corps, chaque jour, des millions de cellules meurent et sont remplac\u00e9es par de nouvelles cellules. Lorsque les cellules meurent, leur ADN est fragment\u00e9 et certains de ces fragments d’ADN atteignent le sang et peuvent \u00eatre d\u00e9tect\u00e9s par des m\u00e9thodes de s\u00e9quen\u00e7age d’ADN. Les cellules mortes contiennent un code chimique unique qui peut nous dire l’identit\u00e9 de la cellule et m\u00eame les processus biologiques et pathologiques qui s’y d\u00e9roulent ainsi que r\u00e9v\u00e9ler une activit\u00e9 cellulaire anormale.<\/p>\n

Les chercheurs ont con\u00e7u un processus pour lire pr\u00e9cis\u00e9ment ces informations \u00e0 partir de l’ADN dans le sang et les utiliser pour d\u00e9terminer la nature de la maladie ou de la tumeur, son emplacement exact dans le corps et m\u00eame son \u00e9volution.<\/p>\n

\u00abGr\u00e2ce \u00e0 ces progr\u00e8s scientifiques, nous avons compris que si ces informations \u00e9taient conserv\u00e9es dans la structure de l’ADN dans le sang, nous pourrions utiliser ces donn\u00e9es pour d\u00e9terminer la source tissulaire des cellules mortes et les g\u00e8nes qui \u00e9taient actifs dans ces m\u00eames cellules. Sur la base de ces r\u00e9sultats, nous pouvons d\u00e9couvrir des d\u00e9tails cl\u00e9s sur la sant\u00e9 du patient<\/em> \u00bb, a expliqu\u00e9 le professeur Friedman. \u00abNous sommes en mesure de mieux comprendre pourquoi les cellules sont mortes, qu\u2019il s\u2019agisse d\u2019une infection ou d\u2019un cancer et, sur cette base, nous sommes mieux plac\u00e9s pour d\u00e9terminer comment la maladie se d\u00e9veloppe<\/em>.\u00bb<\/p>\n

Outre les avantages diagnostiques \u00e9vidents de ce processus, le test est \u00e9galement non invasif et beaucoup moins co\u00fbteux que les biopsies traditionnelles.<\/p>\n

\u00abNous esp\u00e9rons que cette approche permettra un diagnostic plus pr\u00e9coce de la maladie et aidera les m\u00e9decins \u00e0 traiter les patients plus efficacement<\/em>\u00bb, a d\u00e9clar\u00e9 le Dr Ronen Sadeh. \u00abReconna\u00eetre le potentiel de cette approche … peut \u00eatre si b\u00e9n\u00e9fique \u00e0 des fins diagnostiques et th\u00e9rapeutiques<\/em>\u00bb, a d\u00e9clar\u00e9 le Dr Ronen Sadeh, ajoutant qu\u2019une entreprise commerciale avait \u00e9t\u00e9 mise en place en partenariat avec de grandes soci\u00e9t\u00e9s pharmaceutiques pour mener des tests cliniques \u00ab\u00a0dans le but de mettre cette approche innovante \u00e0 la disposition des patients<\/em>\u00a0\u00bb.<\/p>\n

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Des chercheurs de l’Universit\u00e9 h\u00e9bra\u00efque ont mis au point un nouveau test sanguin susceptible de diagnostiquer un large \u00e9ventail de maladies. Par Yakir Benzion, Unis avec Isra\u00ebl \u00catre gravement malade n’est jamais amusant et souvent tr\u00e8s compliqu\u00e9 lorsque des examens invasifs sont n\u00e9cessaires, mais une \u00e9quipe de recherche isra\u00e9lienne a d\u00e9velopp\u00e9 un nouveau test sanguin… Read more »<\/a><\/p>\n","protected":false},"author":4242,"featured_media":378889,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[28414],"tags":[40152,33896,29798,29313,36002,29783],"class_list":["post-378886","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-influence-israelienne","tag-adn-fr","tag-cancer-fr","tag-medecine","tag-recherche","tag-sang","tag-sante"],"better_featured_image":{"id":378889,"alt_text":"","caption":"Shutterstock","description":"","media_type":"image","media_details":{"width":2560,"height":1362,"file":"2021\/02\/shutterstock_408591208-scaled.jpg","sizes":{"medium":{"file":"shutterstock_408591208-300x160.jpg","width":300,"height":160,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_408591208-300x160.jpg"},"large":{"file":"shutterstock_408591208-1024x545.jpg","width":1024,"height":545,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_408591208-1024x545.jpg"},"thumbnail":{"file":"shutterstock_408591208-150x150.jpg","width":150,"height":150,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_408591208-150x150.jpg"},"medium_large":{"file":"shutterstock_408591208-768x409.jpg","width":768,"height":409,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_408591208-768x409.jpg"},"1536x1536":{"file":"shutterstock_408591208-1536x817.jpg","width":1536,"height":817,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_408591208-1536x817.jpg"},"uwi-full-width":{"file":"shutterstock_408591208-780x415.jpg","width":780,"height":415,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_408591208-780x415.jpg"},"uwi-featured-carousel":{"file":"shutterstock_408591208-890x400.jpg","width":890,"height":400,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_408591208-890x400.jpg"},"uwi-featured-content":{"file":"shutterstock_408591208-290x160.jpg","width":290,"height":160,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_408591208-290x160.jpg"},"uwi-content-loop":{"file":"shutterstock_408591208-190x190.jpg","width":190,"height":190,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_408591208-190x190.jpg"},"uwi-category_list":{"file":"shutterstock_408591208-180x100.jpg","width":180,"height":100,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_408591208-180x100.jpg"},"uwi-tiny":{"file":"shutterstock_408591208-40x40.jpg","width":40,"height":40,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_408591208-40x40.jpg"},"uwi-email-featured":{"file":"shutterstock_408591208-250x170.jpg","width":250,"height":170,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_408591208-250x170.jpg"},"uwi-email":{"file":"shutterstock_408591208-200x140.jpg","width":200,"height":140,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_408591208-200x140.jpg"},"uwi-iphone":{"file":"shutterstock_408591208-960x640.jpg","width":960,"height":640,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_408591208-960x640.jpg"},"uwi-iphone-x2":{"file":"shutterstock_408591208-1136x640.jpg","width":1136,"height":640,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_408591208-1136x640.jpg"},"uwi-ipad":{"file":"shutterstock_408591208-1024x768.jpg","width":1024,"height":768,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_408591208-1024x768.jpg"},"uwi-ipad-x2":{"file":"shutterstock_408591208-2048x1536.jpg","width":2048,"height":1536,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2021\/02\/shutterstock_408591208-2048x1536.jpg"},"uwi-full-width-video":{"file":"shutterstock_408591208-779x414.jpg","width":779,"height":414,"mime-type":"image\/jpeg","source_url":"https:\/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