{"id":355368,"date":"2020-07-05T17:01:51","date_gmt":"2020-07-05T14:01:51","guid":{"rendered":"https:\/\/kinsta.unitedwithisrael.org\/?p=355368"},"modified":"2020-07-07T15:59:54","modified_gmt":"2020-07-07T12:59:54","slug":"medecine-les-chercheurs-israeliens-decouvrent-un-lien-entre-maladies-cardiovasculaires-et-cancer","status":"publish","type":"post","link":"https:\/\/kinsta.unitedwithisrael.org\/fr\/medecine-les-chercheurs-israeliens-decouvrent-un-lien-entre-maladies-cardiovasculaires-et-cancer\/","title":{"rendered":"M\u00e9decine: les chercheurs isra\u00e9liens d\u00e9couvrent un lien entre maladies cardiovasculaires et cancer"},"content":{"rendered":"

Les chercheurs du Technion ont d\u00e9couvert qu’un diagnostic pr\u00e9coce des probl\u00e8mes cardiaques chez les patients canc\u00e9reux pourrait am\u00e9liorer consid\u00e9rablement le succ\u00e8s du traitement.<\/strong><\/em><\/p>\n

Par Yakir Benzion, Unis avec Isra\u00ebl<\/em><\/p>\n

Des chercheurs du leader isra\u00e9lien Technion Institute of Technology ont fait une d\u00e9couverte r\u00e9volutionnaire: il existe un lien entre le c\u0153ur et le cancer.<\/p>\n

Une \u00e9quipe dirig\u00e9e par le professeur Ami Aronheim, le professeur Yuval Shaked et le Dr Shimrit Avraham a d\u00e9couvert que des changements pr\u00e9coces dans le c\u0153ur r\u00e9sultant d’une maladie cardiaque ou de l\u00e9sions de l’organe vital chez un patient atteint de cancer pouvaient entra\u00eener la progression du cancer.<\/p>\n

Les r\u00e9sultats pourraient potentiellement aider les cardio-oncologues \u00e0 ralentir la progression du cancer et \u00e0 am\u00e9liorer les r\u00e9sultats du cancer.<\/p>\n

On sait d\u00e9j\u00e0 que le cancer et les maladies cardiovasculaires sont li\u00e9s et que l’insuffisance cardiaque et le stress sont en corr\u00e9lation avec un mauvais pronostic du cancer. Cela est particuli\u00e8rement vrai pour ceux qui sont trait\u00e9s pour un cancer, o\u00f9 les m\u00e9dicaments de chimioth\u00e9rapie peuvent endommager le muscle cardiaque. Cependant, les effets d’une modification de la fonction cardiaque sur le cancer ne sont pas bien connus.<\/p>\n

Les chercheurs ont \u00e9tudi\u00e9 le lien entre les changements cardiaques et le cancer, en recherchant si des changements pr\u00e9coces de la fonction cardiaque en l’absence d’insuffisance cardiaque, appel\u00e9s \u00abremodelage cardiaque\u00bb, favorisaient le cancer.<\/p>\n

Pour reproduire le ph\u00e9nom\u00e8ne de remodelage cardiaque, l’\u00e9quipe de recherche a utilis\u00e9 une technique de laboratoire appel\u00e9e constriction aortique transversale (TAC) pour exercer une pression m\u00e9canique sur le c\u0153ur des souris de laboratoire. La m\u00e9thode entra\u00eene une augmentation de la croissance des cellules cardiaques appel\u00e9e hypertrophie, qui est un effet courant des complications cardiovasculaires.<\/p>\n

L’\u00e9quipe a ensuite implant\u00e9 des cellules canc\u00e9reuses dans les souris op\u00e9r\u00e9es par TAC pour voir si le remodelage cardiaque pr\u00e9coce affectait la progression tumorale.<\/p>\n

Ils ont d\u00e9couvert que les souris d\u00e9veloppaient des tumeurs plus grosses au niveau des cellules canc\u00e9reuses implant\u00e9es, ainsi qu’un taux plus \u00e9lev\u00e9 de cellules canc\u00e9reuses ensemenc\u00e9es dans les poumons, repr\u00e9sentant des m\u00e9tastases (tumeurs secondaires propag\u00e9es \u00e0 partir de la l\u00e9sion d’origine) par rapport aux souris non op\u00e9r\u00e9es.<\/p>\n

Les enqu\u00eateurs ont \u00e9galement constat\u00e9 que les souris op\u00e9r\u00e9es par TAC pr\u00e9sentaient un niveau plus \u00e9lev\u00e9 d’une prot\u00e9ine promotrice de tumeurs appel\u00e9e Periostin, mais une Periostin inf\u00e9rieure corr\u00e9l\u00e9e avec une prolif\u00e9ration des cellules canc\u00e9reuses plus faible.<\/p>\n

Les r\u00e9sultats de l’\u00e9tude, publi\u00e9s dans la revue m\u00e9dicale Circulation, ont montr\u00e9 qu’il existe effectivement un lien entre les maladies cardiovasculaires et le cancer.<\/p>\n

Les r\u00e9sultats soulignent l’importance d’un diagnostic et d’un traitement pr\u00e9coces des maladies cardiaques chez les patients canc\u00e9reux, montrant qu’une intervention pr\u00e9coce avait le potentiel de r\u00e9duire consid\u00e9rablement la progression du cancer et d’am\u00e9liorer les r\u00e9sultats du traitement.<\/p>\n

\u00ab\u00c0 la suite de l’\u00e9tude, nous vous recommandons de traiter les probl\u00e8mes cardiaques t\u00f4t, lorsque le corps r\u00e9sout toujours avec succ\u00e8s le probl\u00e8me, et de ne pas attendre une maladie chronique\u00bb<\/em>, a d\u00e9clar\u00e9 le professeur Aronheim. \u00ab\u00a0De tels probl\u00e8mes peuvent \u00eatre d\u00e9tect\u00e9s avec un simple test d’\u00e9chocardiographie, et dans de nombreux cas, un cath\u00e9t\u00e9risme pr\u00e9coce peut aider \u00e0 ralentir le d\u00e9veloppement canc\u00e9reux.\u00a0\u00bb<\/em><\/p>\n

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Les chercheurs du Technion ont d\u00e9couvert qu’un diagnostic pr\u00e9coce des probl\u00e8mes cardiaques chez les patients canc\u00e9reux pourrait am\u00e9liorer consid\u00e9rablement le succ\u00e8s du traitement. Par Yakir Benzion, Unis avec Isra\u00ebl Des chercheurs du leader isra\u00e9lien Technion Institute of Technology ont fait une d\u00e9couverte r\u00e9volutionnaire: il existe un lien entre le c\u0153ur et le cancer. Une \u00e9quipe… Read more »<\/a><\/p>\n","protected":false},"author":4242,"featured_media":298492,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[28418],"tags":[33896,30739,29798,29313,29783,28846],"class_list":["post-355368","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-actualites-israeliennes","tag-cancer-fr","tag-coeur","tag-medecine","tag-recherche","tag-sante","tag-traitement"],"better_featured_image":{"id":298492,"alt_text":"A researcher at the Technion Israel Institute of Technology in Haifa (Hadas Parush\/Flash90)","caption":"A researcher at the Technion Israel Institute of Technology in Haifa (Hadas Parush\/Flash90)","description":"Pesquisador no Instituto Technion na cidade de Haifa (Hadas 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