{"id":322628,"date":"2019-11-27T13:08:36","date_gmt":"2019-11-27T10:08:36","guid":{"rendered":"https:\/\/kinsta.unitedwithisrael.org\/?p=322628"},"modified":"2019-11-27T16:04:53","modified_gmt":"2019-11-27T13:04:53","slug":"israel-invente-une-puce-qui-lutte-contre-alzheimer","status":"publish","type":"post","link":"https:\/\/kinsta.unitedwithisrael.org\/fr\/israel-invente-une-puce-qui-lutte-contre-alzheimer\/","title":{"rendered":"Isra\u00ebl invente une puce qui lutte contre Alzheimer"},"content":{"rendered":"

La puce vise \u00e0 ins\u00e9rer dans le cerveau un produit chimique cl\u00e9 qui contrecarre l’accumulation anormale de prot\u00e9ines.<\/strong><\/em><\/p>\n

Par l’\u00e9quipe d’Unis avec Isra\u00ebl<\/em><\/p>\n

Des chercheurs de l’institut de technologie Technion-Isra\u00ebl, en partenariat avec l’universit\u00e9 Bar-Ilan, ont r\u00e9cemment cr\u00e9\u00e9 une nouvelle technologie permettant de traiter les patients atteints de la maladie d’Alzheimer de mani\u00e8re \u00e0 emp\u00eacher le d\u00e9veloppement de la maladie.<\/p>\n

L\u2019\u00e9quipe de recherche isra\u00e9lienne a mis au point une puce de silicium \u00e0 l\u2019\u00e9chelle nanom\u00e9trique pouvant contenir des prot\u00e9ines prot\u00e9iques suffisamment petites pour traverser la barri\u00e8re h\u00e9mato-enc\u00e9phalique sans \u00eatre d\u00e9tect\u00e9es.<\/p>\n

La barri\u00e8re h\u00e9mato-enc\u00e9phalique, qui prot\u00e8ge le syst\u00e8me nerveux de toutes les substances \u00e9trang\u00e8res, ne permet pas de diff\u00e9rencier ce qui est bon et ce qui est mauvais, et tente de les emp\u00eacher d’entrer. C’est pourquoi la plupart des m\u00e9dicaments susceptibles de traiter des maladies du cerveau atteignent rarement le cerveau.<\/p>\n

La puce isra\u00e9lienne, cependant, pourrait peut-\u00eatre changer cela.<\/p>\n

La recherche a \u00e9t\u00e9 men\u00e9e par le professeur Ester Segal et Ph.D. l’\u00e9tudiant Michal Rosenberg de la facult\u00e9 de biotechnologie et d’ing\u00e9nierie alimentaire du Technion, et leurs partenaires, le professeur Orit Shefi et le doctorant Neta Zilony-Hanin, \u00e9tudiante \u00e0 la facult\u00e9 de g\u00e9nie de l\u2019Universit\u00e9 Bar Ilan.<\/p>\n

\u00c0 titre de r\u00e9f\u00e9rence, la maladie d\u2019Alzheimer est une maladie d\u00e9g\u00e9n\u00e9rative du cerveau qui entra\u00eene une perte progressive de la m\u00e9moire, du jugement et de la capacit\u00e9 de fonctionner.<\/p>\n

La maladie est principalement caus\u00e9e par l’accumulation de prot\u00e9ines anormales dans le cerveau, ce qui tue les cellules nerveuses et perturbe les processus c\u00e9r\u00e9braux.<\/p>\n

Le traitement de la maladie n\u00e9cessite l’insertion d’une prot\u00e9ine sp\u00e9cifique dans le cerveau, qui compense l’accumulation anormale. Bien que cela soit plus facile \u00e0 dire qu’\u00e0 faire, la nouvelle puce isra\u00e9lienne pourrait le faire de mani\u00e8re coh\u00e9rente.<\/p>\n

Au cours d\u2019une s\u00e9rie d\u2019exp\u00e9riences, nous avons montr\u00e9 \u00e0 des souris que les deux mani\u00e8res d\u2019alimenter la plateforme dans le cerveau aboutissaient au r\u00e9sultat souhait\u00e9 \u00ab\u00a0, a d\u00e9clar\u00e9 Rosenberg.\u00a0\u00bb En outre, notre technologie a \u00e9galement \u00e9t\u00e9 test\u00e9e dans un mod\u00e8le cellulaire de la maladie d\u2019Alzheimer et la lib\u00e9ration de prot\u00e9ines a conduit \u00e0 sauver les cellules nerveuses. \u00ab\u00a0<\/p>\n

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La puce vise \u00e0 ins\u00e9rer dans le cerveau un produit chimique cl\u00e9 qui contrecarre l’accumulation anormale de prot\u00e9ines. Par l’\u00e9quipe d’Unis avec Isra\u00ebl Des chercheurs de l’institut de technologie Technion-Isra\u00ebl, en partenariat avec l’universit\u00e9 Bar-Ilan, ont r\u00e9cemment cr\u00e9\u00e9 une nouvelle technologie permettant de traiter les patients atteints de la maladie d’Alzheimer de mani\u00e8re \u00e0 emp\u00eacher… Read more »<\/a><\/p>\n","protected":false},"author":4242,"featured_media":239290,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[28418],"tags":[36642,29951,30152,34248,30509,36643,29747],"class_list":["post-322628","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-actualites-israeliennes","tag-alzaheimer","tag-cerveau","tag-chercheurs","tag-innovation-fr","tag-medecins","tag-proteines","tag-puce"],"better_featured_image":{"id":239290,"alt_text":"","caption":"(Photo Credit: Tel Aviv University)","description":"","media_type":"image","media_details":{"width":505,"height":270,"hwstring_small":"height='68' 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