{"id":292535,"date":"2019-04-16T09:19:14","date_gmt":"2019-04-16T06:19:14","guid":{"rendered":"https:\/\/kinsta.unitedwithisrael.org\/?p=292535"},"modified":"2019-04-16T12:18:40","modified_gmt":"2019-04-16T09:18:40","slug":"nouvelle-avancee-spectaculaire-israelienne-dans-la-lutte-contre-le-cancer","status":"publish","type":"post","link":"https:\/\/kinsta.unitedwithisrael.org\/fr\/nouvelle-avancee-spectaculaire-israelienne-dans-la-lutte-contre-le-cancer\/","title":{"rendered":"Nouvelle avanc\u00e9e spectaculaire isra\u00e9lienne dans la lutte contre le cancer !"},"content":{"rendered":"

Au cours des derni\u00e8res ann\u00e9es, les scientifiques ont d\u00e9couvert que les prot\u00e9ines li\u00e9es \u00e0 l’ARN jouaient un r\u00f4le important dans la croissance du cancer: ces prot\u00e9ines, actives dans toutes les cellules, mais plus particuli\u00e8rement dans les cellules canc\u00e9reuses, se lient aux mol\u00e9cules d’ARN et acc\u00e9l\u00e8rent ainsi la croissance des tumeurs.<\/strong> <\/em><\/p>\n

Aucun traitement contre le cancer n’a \u00e9t\u00e9 \u00e0 ce jour dirig\u00e9 contre ces prot\u00e9ines. Dans le prochain num\u00e9ro de Nature Communications, le Professeur Rotem Karni et son \u00e9quipe de l\u2019Universit\u00e9 h\u00e9bra\u00efque de J\u00e9rusalem pr\u00e9sentent une nouvelle technologie de lutte contre le cancer.
\nIls ont con\u00e7u des mol\u00e9cules leurres qui permettent aux prot\u00e9ines qui se lient normalement \u00e0 l’ARN de s’unir \u00e0 elles. Une fois li\u00e9es, ces prot\u00e9ines ne peuvent plus se lier aux mol\u00e9cules naturelles d\u2019ARN des cellules canc\u00e9reuses et perdent leur activit\u00e9 de promotion du cancer.
\n\u00ab\u00a0Notre technologie est un nouveau centre de la lutte contre le cancer. En comprenant la fonction biologique des prot\u00e9ines li\u00e9es \u00e0 l’ARN, nous concevons avec succ\u00e8s des mol\u00e9cules leurres qui inhibent ces prot\u00e9ines et nous rapprochent de plus en plus de la cr\u00e9ation d’un m\u00e9dicament anticanc\u00e9reux<\/em> \u00ab\u00a0, a d\u00e9clar\u00e9 Karni.<\/p>\n

Pour tester les leurres lorsqu’ils ont \u00e9t\u00e9 inject\u00e9s dans souris saines, les cellules canc\u00e9reuses ne se sont pas reproduites et peu de temps apr\u00e8s, les tumeurs ont disparu.Bien que cette \u00e9tude ait test\u00e9 l’efficacit\u00e9 des mol\u00e9cules leurres dans les cellules canc\u00e9reuses du sein et du cerveau, Karni a expliqu\u00e9 que leur technologie permettait aux scientifiques de l’adapter.
\n\u00ab\u00a0Nous devons encore examiner la toxicit\u00e9 des mol\u00e9cules de leurre et tester leur efficacit\u00e9 chez les animaux avant de pouvoir les transmettre aux humains<\/em>\u00ab\u00a0, a averti Karni. \u00ab\u00a0Je suis optimiste, car nous avons d\u00e9j\u00e0 r\u00e9ussi \u00e0 cr\u00e9er des leurres qui inhibent les prot\u00e9ines de liaison \u00e0 l’ARN dans d’autres types de cancer.<\/em> \u00ab\u00a0.
\nJusqu’\u00e0 pr\u00e9sent, Yi ssum, la soci\u00e9t\u00e9 de recherche et d\u00e9veloppement de l’universit\u00e9 h\u00e9bra\u00efque, a d\u00e9pos\u00e9 un brevet d\u00e9crivant cette technologie aux \u00c9tats-Unis et en Europe.<\/p>\n

Source: Iton Gadol<\/em><\/p>\n

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Au cours des derni\u00e8res ann\u00e9es, les scientifiques ont d\u00e9couvert que les prot\u00e9ines li\u00e9es \u00e0 l’ARN jouaient un r\u00f4le important dans la croissance du cancer: ces prot\u00e9ines, actives dans toutes les cellules, mais plus particuli\u00e8rement dans les cellules canc\u00e9reuses, se lient aux mol\u00e9cules d’ARN et acc\u00e9l\u00e8rent ainsi la croissance des tumeurs. Aucun traitement contre le cancer… Read more »<\/a><\/p>\n","protected":false},"author":4242,"featured_media":291514,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[28414],"tags":[33896,33895,31464,33894,29313,28846],"class_list":["post-292535","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-influence-israelienne","tag-cancer-fr","tag-cellules","tag-medicament","tag-molecules","tag-recherche","tag-traitement"],"better_featured_image":{"id":291514,"alt_text":"Sheba Medical Center cancer research","caption":"Researcher at Sheba Medical Center (Youtube\/Screenshot)","description":"Researcher at Sheba Medical Center 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