{"id":267956,"date":"2018-08-30T12:02:25","date_gmt":"2018-08-30T09:02:25","guid":{"rendered":"https:\/\/kinsta.unitedwithisrael.org\/?p=267956"},"modified":"2018-08-26T17:13:34","modified_gmt":"2018-08-26T14:13:34","slug":"medecine-une-equipe-israelienne-elabore-un-medicament-contre-la-leucemie","status":"publish","type":"post","link":"https:\/\/kinsta.unitedwithisrael.org\/fr\/medecine-une-equipe-israelienne-elabore-un-medicament-contre-la-leucemie\/","title":{"rendered":"M\u00e9decine: une \u00e9quipe isra\u00e9lienne \u00e9labore un m\u00e9dicament contre la leuc\u00e9mie!"},"content":{"rendered":"

Une \u00e9quipe de l\u2019Universit\u00e9 H\u00e9bra\u00efque de J\u00e9rusalem a r\u00e9alis\u00e9 l\u2019une des plus importantes perc\u00e9es de la recherche sur la leuc\u00e9mie des quarante derni\u00e8res ann\u00e9es, \u00e9laborant pour la premi\u00e8re fois un rem\u00e8de contre la maladie.<\/strong><\/em><\/p>\n

Par: l’\u00e9quipe d’Unis avec Isra\u00ebl<\/em><\/p>\n

Le Dr Yinon Ben-Neriah et son \u00e9quipe de l\u2019Universit\u00e9 H\u00e9bra\u00efque de J\u00e9rusalem offrent une lueur d\u2019espoir aux patients atteints de cancer \u00e0 travers le monde, avec une avanc\u00e9e majeure dans la recherche d\u2019un traitement curatif de la leuc\u00e9mie my\u00e9lo\u00efde aigu\u00eb.<\/p>\n

Plus pr\u00e9cis\u00e9ment, les chercheurs isra\u00e9liens ont mis au point un m\u00e9dicament biologique de pointe ayant d\u00e9j\u00e0 fait ses preuves en permettant un taux de gu\u00e9rison de 50% chez les souris de laboratoire atteintes de leuc\u00e9mie my\u00e9lo\u00efde aigu\u00eb, une forme extr\u00eamement agressive de cancer , et dont le taux de survie s’\u00e9l\u00e8ve g\u00e9n\u00e9ralement \u00e0 25% seulement.<\/p>\n

Le m\u00e9dicament du Dr Ben-Neriah repr\u00e9sente une perc\u00e9e spectaculaire car, contrairement \u00e0 de nombreuses autres formes de cancer pour lesquelles de nouveaux traitements efficaces ont \u00e9t\u00e9 introduits, les quarante derni\u00e8res ann\u00e9es n’ont connu que peu d’avanc\u00e9es en mati\u00e8re de leuc\u00e9mie.<\/p>\n

Les r\u00e9sultats de l’essai ont r\u00e9cemment \u00e9t\u00e9 publi\u00e9s dans Cell, l’une des principales revues sp\u00e9cialis\u00e9es dans les sciences de la vie.<\/p>\n

L’un des plus grands d\u00e9fis du d\u00e9veloppement de m\u00e9dicaments anticanc\u00e9reux biologiques pour traiter la leuc\u00e9mie est leur capacit\u00e9 \u00e0 cibler uniquement des prot\u00e9ines cellulaires leuc\u00e9miques individuelles. Les cellules leuc\u00e9miques, cependant, s\u2019adaptent et r\u00e9agissent en bloquant les m\u00e9dicaments, ce qui se traduit par des cellules canc\u00e9reuses r\u00e9sistantes aux m\u00e9dicaments qui repoussent rapidement, ce qui fait progresser l\u2019impact de a maladie sur le corps du patient.<\/p>\n

Le nouveau m\u00e9dicament de Ben-Neriah r\u00e9volutionne le traitement en agissant comme une bombe \u00e0 fragmentation, attaquant plusieurs prot\u00e9ines leuc\u00e9miques \u00e0 la fois, de sorte que la maladie ne puisse pas surmonter les effets du traitement. La nouvelle th\u00e9rapie fait \u00e9galement le travail d’une approche multi-m\u00e9dicament, qui \u00e9limine l’h\u00f4te d\u00e9bilitant d’effets secondaires provoqu\u00e9s par l’administration simultan\u00e9e de plusieurs th\u00e9rapies pour lutter contre le cancer.<\/p>\n

\u00ab\u00a0Nous \u00e9tions ravis d’observer un changement aussi spectaculaire, m\u00eame apr\u00e8s une seule dose du nouveau m\u00e9dicament. Presque tous les signes de leuc\u00e9mie des souris de laboratoire ont disparu pendant la nuit<\/em> \u00bb, a comment\u00e9 Ben-Neriah.<\/p>\n

En outre, la nouvelle th\u00e9rapie de Ben-Neriah s’est \u00e9galement r\u00e9v\u00e9l\u00e9e prometteuse pour \u00e9radiquer les cellules souches de la leuc\u00e9mie, un exploit qui pourrait permettre de trouver le traitement ultime contre la leuc\u00e9mie aigu\u00eb.<\/p>\n

R\u00e9cemment, BioTheryX a achet\u00e9 les droits de d\u00e9veloppement du m\u00e9dicament et continuera de travailler avec l\u2019\u00e9quipe de recherche de Ben-Neriah, en demandant l\u2019approbation de la FDA pour commencer des \u00e9tudes cliniques chez l\u2019homme.<\/p>\n

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Une \u00e9quipe de l\u2019Universit\u00e9 H\u00e9bra\u00efque de J\u00e9rusalem a r\u00e9alis\u00e9 l\u2019une des plus importantes perc\u00e9es de la recherche sur la leuc\u00e9mie des quarante derni\u00e8res ann\u00e9es, \u00e9laborant pour la premi\u00e8re fois un rem\u00e8de contre la maladie. Par: l’\u00e9quipe d’Unis avec Isra\u00ebl Le Dr Yinon Ben-Neriah et son \u00e9quipe de l\u2019Universit\u00e9 H\u00e9bra\u00efque de J\u00e9rusalem offrent une lueur d\u2019espoir… Read more »<\/a><\/p>\n","protected":false},"author":4242,"featured_media":267889,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[28418],"tags":[30152,17,31463,29306,29798,31464,30873,31465,1011,28846],"class_list":["post-267956","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-actualites-israeliennes","tag-chercheurs","tag-jerusalem","tag-leucemie","tag-maladie","tag-medecine","tag-medicament","tag-soin","tag-souris","tag-test","tag-traitement"],"better_featured_image":{"id":267889,"alt_text":"Dr. Yinon Ben-Neriah (R) and his team at the Hebrew University of Jerusalem. 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