{"id":221187,"date":"2018-05-17T15:49:24","date_gmt":"2018-05-17T12:49:24","guid":{"rendered":"https:\/\/kinsta.unitedwithisrael.org\/?p=221187"},"modified":"2018-05-06T16:27:22","modified_gmt":"2018-05-06T13:27:22","slug":"des-chercheurs-israeliens-developpent-une-methode-pour-detecter-le-cancer-du-sein-a-un-stade-precoce","status":"publish","type":"post","link":"https:\/\/kinsta.unitedwithisrael.org\/fr\/des-chercheurs-israeliens-developpent-une-methode-pour-detecter-le-cancer-du-sein-a-un-stade-precoce\/","title":{"rendered":"Des chercheurs isra\u00e9liens d\u00e9veloppent une m\u00e9thode pour d\u00e9tecter le cancer du sein \u00e0 un stade pr\u00e9coce"},"content":{"rendered":"

Des chercheurs de l’Universit\u00e9 Ben Gourion dans le Neguev et du centre m\u00e9dical de l’Universit\u00e9 Soroka \u00e0 Beer Sheva ont annonc\u00e9 le d\u00e9veloppement d’une m\u00e9thode nouvelle et pr\u00e9cise de d\u00e9tection du cancer pr\u00e9coce du sein, utilisant une technologie peu co\u00fbteuse pour analyser l’haleine et les urines.<\/strong><\/em><\/p>\n

Par: Israel 21c<\/a><\/em><\/p>\n

L’\u00e9quipe de chercheurs isra\u00e9liens a utilis\u00e9 deux capteurs de gaz \u00ab\u00a0nez \u00e9lectroniques\u00a0\u00bb diff\u00e9rents, ainsi que la spectom\u00e9trie de masse par chromatographie en phae gazeuse pour isoler les donn\u00e9es pertinentes et identifier avec davantage de pr\u00e9cision les biomarqueurs du cancer, a annonc\u00e9 l’Universit\u00e9 Ben Gourion.<\/p>\n

A travers leur \u00e9tude, publi\u00e9e dans \u00ab\u00a0Computers in Biology and Medicine\u00a0\u00bb, les chercheurs ont pu d\u00e9tecter le cancer du sein avec une pr\u00e9cision de plus de 95% en moyenne, en utilisant de nez \u00e9lectroniques diff\u00e9rents, qui ont identifi\u00e9 des cycles respiratoires uniques chez les femmes atteintes par le cancer du sein.<\/p>\n

De plus, les chercheurs ont d\u00e9clar\u00e9 que leurs analyses statistiques d’\u00e9chantillons d’urine remani\u00e9s, soumis tant par des patients en bonne sant\u00e9 que par des personnes souffrant du cancer du sein, avaient abouti \u00e0 une pr\u00e9cision moyenne de 85%.<\/p>\n

\u00ab\u00a0Le fait de survivre au cancer du sein est solidement li\u00e9 \u00e0 la sensibilit\u00e9 de la d\u00e9tection des tumeurs: des m\u00e9thodes pr\u00e9cises visant \u00e0 d\u00e9tecter des tumeurs plus petites et plus pr\u00e9coces restent une priorit\u00e9<\/em>\u00ab\u00a0, a d\u00e9clar\u00e9 le Professeur Yehuda Zeiri, membre du d\u00e9partement d\u2019Ing\u00e9nierie Biom\u00e9dicale de l’Universit\u00e9 Ben Gourion, qui a particip\u00e9 \u00e0 l’\u00e9tude. \u00ab\u00a0Notre nouvelle approche utilisant des \u00e9chantillons d’urine et d’haleine expir\u00e9e, analys\u00e9s par des syst\u00e8mes peu on\u00e9reux, et disponibles dans le commerce, est non invasive, accessible, et peut \u00eatre facilement mise en oeuvre dans une vari\u00e9t\u00e9 de param\u00e8tres\u00a0\u00bb<\/em>.<\/p>\n

Une femme sur huit affect\u00e9e<\/h2>\n

D’apr\u00e8s l’Organisation Mondiale de la Sant\u00e9, le cancer du sein est le cancer le plus souvent diagnostiqu\u00e9 chez les femmes \u00e0 travers le monde, et touche une femme sur huit aux Etats-Unis. Il constitue la seconde cause de d\u00e9c\u00e8s par cancer chez les femmes.<\/p>\n

Bien qu’il ait \u00e9t\u00e9 prouv\u00e9 que les mammographies r\u00e9duisent de mani\u00e8re significative le taux de mortalit\u00e9 li\u00e9 au cancer du sein, elles ne sont pas toujours capables de d\u00e9tecter des petites tumeurs parmi des tissus mammaires denses, ont expliqu\u00e9 les chercheurs. En r\u00e9alit\u00e9, la sensibilit\u00e9 typique d’une mammographie, d’une pr\u00e9cision comprise entre 75 et 85%, chute \u00e0 30 \u00e0 50% dans le cas de femmes pr\u00e9sentant des tissus mammaires denses.<\/p>\n

La d\u00e9tection d’imagerie diagnostique actuellement utilis\u00e9e pour les plus petites tumeurs pr\u00e9sente d’importants inconv\u00e9nients, ont d\u00e9clar\u00e9 les chercheurs. La mammographie \u00e0 \u00e9nergie duale est efficace mais augmente l’exposition aux radiations, et lRM co\u00fbte cher. Les autres m\u00e9thodes telles que la biopsie et l’identification des biomarqueurs s\u00e9riques sont invasives, n\u00e9cessitent beaucoup d’\u00e9quipements et une expertise significative, ont-ils dit.<\/p>\n

\u00ab\u00a0Nous avons d\u00e9sormais d\u00e9montr\u00e9 que des nez \u00e9lectroniques pr\u00e9sents dans le commerce et peu co\u00fbteux suffisaient pour d\u00e9tecter les patients atteints du cancer \u00e0 un stade pr\u00e9coce<\/em>\u00ab\u00a0, a d\u00e9clar\u00e9 Zeiri. \u00ab\u00a0Avec davantage d’\u00e9tudes, il pourra \u00e9galement \u00eatre possible d’analyser des \u00e9chantillons d’urine et de l’haleine expir\u00e9e pour identifier d’autres types de cancers<\/em>\u00ab\u00a0.<\/p>\n

D’autres personnes ont contribu\u00e9 \u00e0 l’\u00e9tude, parmi lesquelles les chercheurs en ing\u00e9nierie biom\u00e9dicale de l’Universit\u00e9 Ben Gourion Or Herman-Saffar, Zvi Boger et Raphael Gonen, le Docteur Shai Libson, chirurgien au sein du Centre de Sant\u00e9 du Sein \u00e0 Soroka, et le Docteur David Lieberman, professeur associ\u00e9 de l’Universit\u00e9 Ben Gourion (…).<\/p>\n

D’autres nez en cours de d\u00e9veloppement en Isra\u00ebl<\/h2>\n

Au sein de l’Institut de Technologie du Technion \u00e0 Ha\u00effa, le Professeur Hossam Haick a d\u00e9velopp\u00e9 NaNose, un nez artificiel de nanotechnologie, au cours des dix derni\u00e8res ann\u00e9es. NaNose a d\u00e9tect\u00e9 avec succ\u00e8s un cancer du poumon \u00e0 un stade avanc\u00e9 et un cancer de l’estomac au cours d’\u00e9tudes cliniques. D\u00e9sormais, l’\u00e9quipe d’Haick travaille \u00e0 d\u00e9tecter le cancer \u00e0 un stage pr\u00e9coce, voire le risque de cancer, en utilisant les analyses d’haleine de NaNose.<\/p>\n

Le Professeur David (Didi) Margulies et son groupe de chimie organique de l’Institut Weizmann de Sciences \u00e0 Rehovot a cr\u00e9\u00e9 un nez artificiel de taille nano combinant un ensemble de capteurs sur une seule mol\u00e9cule. Le petit nez peut sentir diff\u00e9rentes mol\u00e9cules de l’environnement et combiner ces informations dans un \u00ab\u00a0parfum\u00a0\u00bb, pouvant \u00ab\u00a0sentir\u00a0\u00bb l’int\u00e9rieur de cellules vivantes.<\/p>\n

\u00ab\u00a0Cela pourrait nous offrir un nouvel outil d’analyse pour fournir des informations auxquelles nous n’avons pas acc\u00e8s aujourd’hui, sur la composition chimique de micro-environnements et cellules<\/em>\u00ab\u00a0, a d\u00e9clar\u00e9 Margulies. Ses recherches ont r\u00e9cemment \u00e9t\u00e9 publi\u00e9es dans Nature Nanotechnology.<\/p>\n

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Des chercheurs de l’Universit\u00e9 Ben Gourion dans le Neguev et du centre m\u00e9dical de l’Universit\u00e9 Soroka \u00e0 Beer Sheva ont annonc\u00e9 le d\u00e9veloppement d’une m\u00e9thode nouvelle et pr\u00e9cise de d\u00e9tection du cancer pr\u00e9coce du sein, utilisant une technologie peu co\u00fbteuse pour analyser l’haleine et les urines. Par: Israel 21c L’\u00e9quipe de chercheurs isra\u00e9liens a utilis\u00e9… Read more »<\/a><\/p>\n","protected":false},"author":4242,"featured_media":211512,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[28414],"tags":[30157,29590,2559,30152,30156,29798,30154,29313,30153,30155],"class_list":["post-221187","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-influence-israelienne","tag-analyse","tag-ben-gourion","tag-cancer","tag-chercheurs","tag-haleine","tag-medecine","tag-nez-electronique","tag-recherche","tag-seins","tag-urine"],"better_featured_image":{"id":211512,"alt_text":"Cancer immunotherapy research","caption":"Cancer immunotherapy research with cell and test tube. 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