{"id":454058,"date":"2023-06-13T07:38:44","date_gmt":"2023-06-13T07:38:44","guid":{"rendered":"https:\/\/kinsta.unitedwithisrael.org\/?p=454058"},"modified":"2023-06-13T10:38:44","modified_gmt":"2023-06-13T07:38:44","slug":"una-nueva-tecnologia-israeli-ayuda-a-predecir-mejor-la-respuesta-del-paciente-a-la-inmunoterapia","status":"publish","type":"post","link":"https:\/\/kinsta.unitedwithisrael.org\/es\/una-nueva-tecnologia-israeli-ayuda-a-predecir-mejor-la-respuesta-del-paciente-a-la-inmunoterapia\/","title":{"rendered":"Una nueva tecnolog\u00eda israel\u00ed ayuda a predecir mejor la respuesta del paciente a la inmunoterapia"},"content":{"rendered":"

Investigadores de la Universidad Ben-Gurion desarrollan un biosensor innovador y se asocian con la empresa de biotecnolog\u00eda israel\u00ed OncoHost para obtener la aprobaci\u00f3n de la FDA.<\/strong><\/p>\n

Fuente: Aurora<\/p>\n

Investigadores de la Universidad Ben Gurion desarrollaron una nueva tecnolog\u00eda de biodetecci\u00f3n que predice la respuesta de los pacientes con c\u00e1ncer a la inmunoterapia con inhibidores del punto de control inmunitario.<\/p>\n

La misma posee el potencial de mejorar la eficacia de la inmunoterapia y evitar la toxicidad y efectos secundarios debilitantes de los pacientes.<\/p>\n

El bioensayo lo desarrollaron los profesores Moshe Elkabets y \u00c1ngel Porfador de la facultad de Ciencias de la Salud de la universidad. Los resultados del estudio se publicaron en la revista Science Advances.<\/p>\n

La nueva tecnolog\u00eda Inmuno-checkpoint Artificial Reporter fue licenciada a OncoHost, una empresa de oncolog\u00eda que Israel guio, y buscar\u00e1 la aprobaci\u00f3n de la Administraci\u00f3n de Drogas y Alimentos de Estados Unidos. El director ejecutivo de OncoHost Ofer Sharon le dijo a The Times of Israel que espera que los ensayos cl\u00ednicos comiencen en seis u ocho meses y espera que el producto llegue al mercado en no m\u00e1s de dos a\u00f1os.<\/p>\n

ICI es uno de los varios tipos de inmunoterapia. Implica la introducci\u00f3n de f\u00e1rmacos de anticuerpos monoclonales mediante infusi\u00f3n en una vena. Se dise\u00f1aron para descomponer los \u201cpuntos de control\u201d de prote\u00ednas que crean las c\u00e9lulas cancerosas para protegerse de los anticuerpos que buscan destruirlas.<\/p>\n

\u201cLa terapia previene la capacidad del tumor para escapar de la inmunidad antitumoral\u201d, explic\u00f3 Elkabets. Antes exist\u00edan biomarcadores para predecir el \u00e9xito de la ICI en un paciente, pero estas pruebas solo ten\u00edan una respuesta del 10-15%, seg\u00fan Elkabets. \u201cLa diferencia con nuestro bioensayo es que busca la funcionalidad. Las otras tecnolog\u00edas buscaban solo la expresi\u00f3n de prote\u00ednas\u201d, dijo Elkabets.<\/p>\n

El equipo de BGU pudo cuantificar la funcionalidad de la prote\u00edna en un tejido fijado o en una muestra de patolog\u00eda antigua. Esta es una ventaja sobre las tecnolog\u00edas actuales que implican la detecci\u00f3n de muestras de tejido fresco. Significa que los pacientes deben someterse a varias biopsias a lo largo del tiempo.<\/p>\n

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\"Donate<\/a><\/div><\/ad-shortcode><\/non-auwi>","protected":false},"excerpt":{"rendered":"

Investigadores de la Universidad Ben-Gurion desarrollan un biosensor innovador y se asocian con la empresa de biotecnolog\u00eda israel\u00ed OncoHost para obtener la aprobaci\u00f3n de la FDA.<\/p>\n","protected":false},"author":47,"featured_media":249923,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[211],"tags":[],"class_list":["post-454058","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-luz-para-las-naciones"],"better_featured_image":{"id":249923,"alt_text":"","caption":"(Photo; shutterstock)","description":"","media_type":"image","media_details":{"width":1000,"height":657,"file":"2015\/01\/shutterstock_165062033.jpg","sizes":{"thumbnail":{"file":"shutterstock_165062033-150x150.jpg","width":150,"height":150,"mime-type":"image\/jpeg","ewww_image_optimizer":"No savings - 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