{"id":437603,"date":"2022-09-24T07:15:46","date_gmt":"2022-09-24T04:15:46","guid":{"rendered":"https:\/\/kinsta.unitedwithisrael.org\/?p=437603"},"modified":"2022-09-28T12:51:07","modified_gmt":"2022-09-28T09:51:07","slug":"una-nueva-investigacion-israeli-puede-producir-un-tratamiento-para-detener-el-parkinson","status":"publish","type":"post","link":"https:\/\/kinsta.unitedwithisrael.org\/es\/una-nueva-investigacion-israeli-puede-producir-un-tratamiento-para-detener-el-parkinson\/","title":{"rendered":"Una nueva investigaci\u00f3n israel\u00ed puede producir un tratamiento para detener el Parkinson"},"content":{"rendered":"

Un estudio de la Universidad de Haifa identifica procesos neuronales comunes de los tipos de enfermedad de Parkinson por primera vez; podr\u00eda ayudar al diagn\u00f3stico precoz.<\/span><\/strong><\/em><\/p>\n

Por Abigail Klein Leichman, <\/span>Israel21c<\/span><\/a><\/em><\/p>\n

Cient\u00edficos de la Universidad de Haifa informaron en la revista <\/span>NJP Parkinson’s Disease<\/span><\/em> de un descubrimiento innovador que podr\u00eda conducir a tratamientos que detengan la propagaci\u00f3n de la enfermedad de Parkinson.<\/span><\/p>\n

Los pacientes de Parkinson sufren una p\u00e9rdida masiva de c\u00e9lulas nerviosas en una regi\u00f3n del cerebro que normalmente est\u00e1 repleta de neuronas dopamin\u00e9rgicas. La dopamina permite que las c\u00e9lulas cerebrales transfieran mensajes y orquesten acciones motoras.<\/span><\/p>\n

Uno de los problemas en el desarrollo de f\u00e1rmacos para la enfermedad es que s\u00f3lo el 15 por ciento de los casos de Parkinson son causados \u200b\u200bpor factores gen\u00e9ticos conocidos. El otro 85% se define como \u201cespor\u00e1dico\u201d y no es posible crear un modelo para el Parkinson espor\u00e1dico en animales.<\/span><\/p>\n

El equipo de investigaci\u00f3n internacional, dirigido por la <\/span>profesora Shani Stern<\/span><\/a> del Departamento de Neurobiolog\u00eda de Sagol de la universidad, utiliz\u00f3 una innovadora t\u00e9cnica de reprogramaci\u00f3n celular para identificar procesos neuronales defectuosos comunes a ambos tipos de enfermedad cerebral progresiva.<\/span><\/p>\n

\u201cLogramos mostrar por primera vez la presencia de mecanismos neuronales y celulares deteriorados de manera similar en todos los tipos de enfermedades que examinamos\u201d, explic\u00f3 Stern.<\/span><\/p>\n

Explic\u00f3 que estos cambios existen en los pacientes de Parkinson mucho antes de que se den cuenta del problema.<\/span><\/p>\n

\u201cSi realizamos esta secuenciaci\u00f3n en una persona joven y encontramos una imagen similar a la que se encuentra entre las personas que han desarrollado la enfermedad de Parkinson, podemos suponer que esta persona desarrollar\u00e1 la enfermedad en una etapa posterior\u201d, dijo.<\/span><\/p>\n

\u201cActualmente, la mayor\u00eda de los tratamientos est\u00e1n destinados a prevenir la agudizaci\u00f3n de la enfermedad m\u00e1s que a prevenirla. Si podemos identificar el potencial para desarrollar la enfermedad de Parkinson en una etapa temprana y desarrollar tratamientos que puedan detener el avance de la enfermedad, podremos comenzar un tratamiento preventivo en una etapa en la que la mortalidad de las c\u00e9lulas nerviosas sea limitada. Esto nos permitir\u00e1 ralentizar significativamente la progresi\u00f3n de la enfermedad\u201d, concluy\u00f3.<\/span><\/p>\n

El equipo de Stern incluy\u00f3 al Prof. Fred Gage del Instituto Salk; Prof. Alexis Brice de ICM, Par\u00eds; Prof. Juergen Winkler de FAU, Alemania; y el Prof. Irit Sagi del Instituto de Ciencias Weizmann.<\/span><\/p>\n

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Un estudio de la Universidad de Haifa identifica procesos neuronales comunes de los tipos de enfermedad de Parkinson por primera vez; podr\u00eda ayudar al diagn\u00f3stico precoz.<\/p>\n","protected":false},"author":47,"featured_media":437633,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[211],"tags":[8395],"class_list":["post-437603","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-luz-para-las-naciones","tag-parkinson-es"],"better_featured_image":{"id":437633,"alt_text":"","caption":"(Shutterstock)","description":"","media_type":"image","media_details":{"width":1031,"height":673,"file":"2022\/09\/Captura-73.png","filesize":1043502,"sizes":{"medium":{"file":"Captura-73-300x196.png","width":300,"height":196,"mime-type":"image\/png","filesize":74769,"source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2022\/09\/Captura-73-300x196.png"},"large":{"file":"Captura-73-1024x668.png","width":1024,"height":668,"mime-type":"image\/png","filesize":481037,"source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2022\/09\/Captura-73-1024x668.png"},"thumbnail":{"file":"Captura-73-150x150.png","width":150,"height":150,"mime-type":"image\/png","filesize":37327,"source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2022\/09\/Captura-73-150x150.png"},"medium_large":{"file":"Captura-73-768x501.png","width":768,"height":501,"mime-type":"image\/png","filesize":318611,"source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2022\/09\/Captura-73-768x501.png"},"uwi-full-width":{"file":"Captura-73-780x509.png","width":780,"height":509,"mime-type":"image\/png","filesize":325986,"source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2022\/09\/Captura-73-780x509.png"},"uwi-featured-carousel":{"file":"Captura-73-890x400.png","width":890,"height":400,"mime-type":"image\/png","filesize":277972,"source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2022\/09\/Captura-73-890x400.png"},"uwi-featured-content":{"file":"Captura-73-290x160.png","width":290,"height":160,"mime-type":"image\/png","filesize":60660,"source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2022\/09\/Captura-73-290x160.png"},"uwi-content-loop":{"file":"Captura-73-190x190.png","width":190,"height":190,"mime-type":"image\/png","filesize":54711,"source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2022\/09\/Captura-73-190x190.png"},"uwi-category_list":{"file":"Captura-73-180x100.png","width":180,"height":100,"mime-type":"image\/png","filesize":28116,"source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2022\/09\/Captura-73-180x100.png"},"uwi-tiny":{"file":"Captura-73-40x40.png","width":40,"height":40,"mime-type":"image\/png","filesize":3945,"source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2022\/09\/Captura-73-40x40.png"},"uwi-email-featured":{"file":"Captura-73-250x170.png","width":250,"height":170,"mime-type":"image\/png","filesize":58070,"source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2022\/09\/Captura-73-250x170.png"},"uwi-email":{"file":"Captura-73-200x140.png","width":200,"height":140,"mime-type":"image\/png","filesize":41913,"source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2022\/09\/Captura-73-200x140.png"},"uwi-iphone":{"file":"Captura-73-960x640.png","width":960,"height":640,"mime-type":"image\/png","filesize":448782,"source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2022\/09\/Captura-73-960x640.png"},"uwi-iphone-x2":{"file":"Captura-73-1031x640.png","width":1031,"height":640,"mime-type":"image\/png","filesize":470327,"source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2022\/09\/Captura-73-1031x640.png"},"uwi-ipad":{"file":"Captura-73-1024x673.png","width":1024,"height":673,"mime-type":"image\/png","filesize":489168,"source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2022\/09\/Captura-73-1024x673.png"},"uwi-full-width-video":{"file":"Captura-73-779x509.png","width":779,"height":509,"mime-type":"image\/png","filesize":325987,"source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2022\/09\/Captura-73-779x509.png"},"uwi-fb-share-video":{"file":"Captura-73-600x315.png","width":600,"height":315,"mime-type":"image\/png","filesize":179204,"source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2022\/09\/Captura-73-600x315.png"},"uwi-fb-share":{"file":"Captura-73-600x320.png","width":600,"height":320,"mime-type":"image\/png","filesize":182056,"source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2022\/09\/Captura-73-600x320.png"},"uwi-featured-content-video":{"file":"Captura-73-289x159.png","width":289,"height":159,"mime-type":"image\/png","filesize":60137,"so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