{"id":428815,"date":"2022-06-20T05:49:42","date_gmt":"2022-06-20T05:49:42","guid":{"rendered":"https:\/\/kinsta.unitedwithisrael.org\/?p=428815"},"modified":"2022-06-20T08:49:42","modified_gmt":"2022-06-20T05:49:42","slug":"cientificos-de-israel-buscan-un-tratamiento-unico-para-el-virus-del-vih","status":"publish","type":"post","link":"https:\/\/kinsta.unitedwithisrael.org\/es\/cientificos-de-israel-buscan-un-tratamiento-unico-para-el-virus-del-vih\/","title":{"rendered":"Cient\u00edficos de Israel buscan un tratamiento \u00fanico para el virus del VIH"},"content":{"rendered":"

Un nuevo enfoque ofrece la esperanza de una vacuna o una terapia que funcione con apenas una sola inyecci\u00f3n.<\/strong><\/em><\/p>\n

Por Abigail Klein Leichman<\/p>\n

As\u00ed lo revel\u00f3 un nuevo estudio de investigaci\u00f3n internacional.<\/p>\n

En las \u00faltimas dos d\u00e9cadas, los tratamientos que cambiaron la enfermedad de letal a cr\u00f3nica permitieron que muchos pacientes con VIH vivan m\u00e1s tiempo. Sin embargo, todav\u00eda no existe una cura permanente.<\/p>\n

La nueva investigaci\u00f3n publicada en la revista Nature, fue dirigida por el bi\u00f3logo molecular Adi Barzel y el estudiante de doctorado Alessio Nehmad de la escuela de neurobiolog\u00eda, bioqu\u00edmica y biof\u00edsica de la Universidad de Tel Aviv en colaboraci\u00f3n con el Centro M\u00e9dico Tel Aviv Sourasky e investigadores adicionales de Israel y EEUU.<\/p>\n

La inyecci\u00f3n \u00fanica fue desarrollada en el laboratorio de Barzel con el uso de gl\u00f3bulos blancos tipo B que ser\u00edan modificados gen\u00e9ticamente dentro del cuerpo del paciente para secretar anticuerpos neutralizantes contra el virus del VIH que causa la enfermedad.<\/p>\n

Formadas en la m\u00e9dula \u00f3sea, las c\u00e9lulas B son responsables de generar anticuerpos contra virus, bacterias y m\u00e1s. Cuando maduran, pasan al sistema sangu\u00edneo y linf\u00e1tico de todo el cuerpo.<\/p>\n

\u201cHasta ahora, solo unos pocos cient\u00edficos -nosotros entre ellos- hab\u00edamos podido dise\u00f1ar c\u00e9lulas B fuera del cuerpo. En este estudio fuimos los primeros en hacer esto en el cuerpo y hacer que estas c\u00e9lulas generaran las B deseadas\u201d, explic\u00f3 Barzel.<\/p>\n

La ingenier\u00eda gen\u00e9tica se realiza con portadores virales derivados de virus que fueron dise\u00f1ados no para causar da\u00f1o sino para llevar el gen codificado para anticuerpo a las c\u00e9lulas B en el cuerpo.<\/p>\n

\u201cEn este caso pudimos introducir con precisi\u00f3n los anticuerpos en un sitio deseado en el genoma de las c\u00e9lulas B\u201d, a\u00f1adi\u00f3 el cient\u00edfico.<\/p>\n

Todos los animales modelo que recibieron el tratamiento respondieron bien y tuvieron grandes cantidades del anticuerpo deseado en la sangre.<\/p>\n

Barzel indic\u00f3 que su equipo produjo el anticuerpo a partir de la sangre y se asegur\u00f3 de que fuera realmente eficaz para neutralizar el virus del VIH en la placa de laboratorio.<\/p>\n

En la actualidad, no existe un tratamiento gen\u00e9tico para el VIH por lo que las oportunidades de investigaci\u00f3n son enormes.<\/p>\n

\u201cCuando las c\u00e9lulas B dise\u00f1adas se encuentran con el virus, \u00e9ste las estimula y las alienta a dividirse, por lo que usamos la causa misma de la enfermedad para combatirla. Adem\u00e1s, si el virus cambia, las c\u00e9lulas B tambi\u00e9n cambiar\u00e1n en consecuencia para combatirlo, por lo que hemos creado el primer medicamento que puede evolucionar en el cuerpo y derrotar a los virus en la \u2018carrera armamentista\u2019\u201d, dijo Barzel.<\/p>\n

El especialista expres\u00f3 tambi\u00e9n que, usando el estudio como base, su equipo espera poder producir un medicamento para el VIH, enfermedades infecciosas adicionales y ciertos tipos de c\u00e1ncer causados \u200b\u200bpor un virus como el de cuello uterino, cabeza y c\u00e1ncer de cuello.<\/p>\n

\u201cEste tratamiento innovador tiene el potencial de lograr una gran mejora en la condici\u00f3n de los pacientes\u201d, finaliz\u00f3.<\/p>\n

Fuente: ISRAEL21c<\/p>\n

\"Donate<\/a><\/div><\/ad-shortcode><\/non-auwi>\n

Do You Love Israel? Make a Donation - Show Your Support!<\/h2>
\"\"<\/a>

<\/p><\/div>

Donate to vital charities<\/strong><\/a> that help protect Israeli citizens and inspire millions around the world to support Israel too! <\/p>

Now more than ever, Israel needs your help to fight and win the war -- including on the battlefield of public opinion. <\/p>

Antisemitism, anti-Israel bias and boycotts are out of control. Israel's enemies are inciting terror and violence against innocent Israelis and Jews around the world. Help us fight back!<\/strong><\/a> <\/p>

STAND WTH ISRAEL - MAKE A DONATION TODAY!<\/a><\/strong><\/p><\/div><\/shortcode>

\"Donate<\/a><\/div><\/ad-shortcode><\/non-auwi>","protected":false},"excerpt":{"rendered":"

Un nuevo enfoque ofrece la esperanza de una vacuna o una terapia que funcione con apenas una sola inyecci\u00f3n.<\/p>\n","protected":false},"author":47,"featured_media":369050,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[211],"tags":[28294,44088,44087],"class_list":["post-428815","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-luz-para-las-naciones","tag-cientificos-de-israel","tag-vih-es","tag-virus-del-vih"],"better_featured_image":{"id":369050,"alt_text":"","caption":"(Shutterstock)","description":"","media_type":"image","media_details":{"width":1000,"height":558,"file":"2020\/11\/shutterstock_1622665819.jpg","sizes":{"medium":{"file":"shutterstock_1622665819-300x167.jpg","width":300,"height":167,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2020\/11\/shutterstock_1622665819-300x167.jpg"},"thumbnail":{"file":"shutterstock_1622665819-150x150.jpg","width":150,"height":150,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2020\/11\/shutterstock_1622665819-150x150.jpg"},"medium_large":{"file":"shutterstock_1622665819-768x429.jpg","width":768,"height":429,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2020\/11\/shutterstock_1622665819-768x429.jpg"},"uwi-full-width":{"file":"shutterstock_1622665819-780x435.jpg","width":780,"height":435,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2020\/11\/shutterstock_1622665819-780x435.jpg"},"uwi-featured-carousel":{"file":"shutterstock_1622665819-890x400.jpg","width":890,"height":400,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2020\/11\/shutterstock_1622665819-890x400.jpg"},"uwi-featured-content":{"file":"shutterstock_1622665819-290x160.jpg","width":290,"height":160,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2020\/11\/shutterstock_1622665819-290x160.jpg"},"uwi-content-loop":{"file":"shutterstock_1622665819-190x190.jpg","width":190,"height":190,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2020\/11\/shutterstock_1622665819-190x190.jpg"},"uwi-category_list":{"file":"shutterstock_1622665819-180x100.jpg","width":180,"height":100,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2020\/11\/shutterstock_1622665819-180x100.jpg"},"uwi-tiny":{"file":"shutterstock_1622665819-40x40.jpg","width":40,"height":40,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2020\/11\/shutterstock_1622665819-40x40.jpg"},"uwi-email-featured":{"file":"shutterstock_1622665819-250x170.jpg","width":250,"height":170,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2020\/11\/shutterstock_1622665819-250x170.jpg"},"uwi-email":{"file":"shutterstock_1622665819-200x140.jpg","width":200,"height":140,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2020\/11\/shutterstock_1622665819-200x140.jpg"},"uwi-iphone":{"file":"shutterstock_1622665819-960x558.jpg","width":960,"height":558,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2020\/11\/shutterstock_1622665819-960x558.jpg"},"uwi-full-width-video":{"file":"shutterstock_1622665819-779x435.jpg","width":779,"height":435,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2020\/11\/shutterstock_1622665819-779x435.jpg"},"uwi-fb-share-video":{"file":"shutterstock_1622665819-600x315.jpg","width":600,"height":315,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2020\/11\/shutterstock_1622665819-600x315.jpg"},"uwi-fb-share":{"file":"shutterstock_1622665819-600x320.jpg","width":600,"height":320,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2020\/11\/shutterstock_1622665819-600x320.jpg"},"uwi-featured-content-video":{"file":"shutterstock_1622665819-289x159.jpg","width":289,"height":159,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2020\/11\/shutterstock_1622665819-289x159.jpg"},"uwi-content-loop-video":{"file":"shutterstock_1622665819-189x189.jpg","width":189,"height":189,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2020\/11\/shutterstock_1622665819-189x189.jpg"},"uwi-category_list-video":{"file":"shutterstock_1622665819-179x99.jpg","width":179,"height":99,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2020\/11\/shutterstock_1622665819-179x99.jpg"},"uwi-tiny-video":{"file":"shutterstock_1622665819-39x39.jpg","width":39,"height":39,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2020\/11\/shutterstock_1622665819-39x39.jpg"},"uwi-email-featured-video":{"file":"shutterstock_1622665819-249x169.jpg","width":249,"height":169,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2020\/11\/shutterstock_1622665819-249x169.jpg"},"uwi-email-video":{"file":"shutterstock_1622665819-209x139.jpg","width":209,"height":139,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2020\/11\/shutterstock_1622665819-209x139.jpg"},"uwi-iphone-video":{"file":"shutterstock_1622665819-959x558.jpg","width":959,"height":558,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2020\/11\/shutterstock_1622665819-959x558.jpg"},"post-thumbnail":{"file":"shutterstock_1622665819-125x125.jpg","width":125,"height":125,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2020\/11\/shutterstock_1622665819-125x125.jpg"}},"image_meta":{"aperture":"0","credit":"","camera":"","caption":"","created_timestamp":"0","copyright":"","focal_length":"0","iso":"0","shutter_speed":"0","title":"","orientation":"1","keywords":[]}},"post":369049,"source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2020\/11\/shutterstock_1622665819.jpg"},"aioseo_notices":[],"distributor_meta":false,"distributor_terms":false,"distributor_media":false,"distributor_original_site_name":"Unidos con Israel","distributor_original_site_url":"https:\/\/kinsta.unitedwithisrael.org\/es\/","push-errors":false,"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/kinsta.unitedwithisrael.org\/es\/wp-json\/wp\/v2\/posts\/428815","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/kinsta.unitedwithisrael.org\/es\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/kinsta.unitedwithisrael.org\/es\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/kinsta.unitedwithisrael.org\/es\/wp-json\/wp\/v2\/users\/47"}],"replies":[{"embeddable":true,"href":"https:\/\/kinsta.unitedwithisrael.org\/es\/wp-json\/wp\/v2\/comments?post=428815"}],"version-history":[{"count":0,"href":"https:\/\/kinsta.unitedwithisrael.org\/es\/wp-json\/wp\/v2\/posts\/428815\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/kinsta.unitedwithisrael.org\/es\/wp-json\/wp\/v2\/media\/369050"}],"wp:attachment":[{"href":"https:\/\/kinsta.unitedwithisrael.org\/es\/wp-json\/wp\/v2\/media?parent=428815"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/kinsta.unitedwithisrael.org\/es\/wp-json\/wp\/v2\/categories?post=428815"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/kinsta.unitedwithisrael.org\/es\/wp-json\/wp\/v2\/tags?post=428815"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}