{"id":370639,"date":"2020-11-25T20:52:50","date_gmt":"2020-11-25T17:52:50","guid":{"rendered":"https:\/\/kinsta.unitedwithisrael.org\/?p=370639"},"modified":"2020-11-26T12:11:54","modified_gmt":"2020-11-26T09:11:54","slug":"avance-israeli-contra-la-diabetes-la-primera-pildora-de-insulina-comienza-los-ensayos-finales","status":"publish","type":"post","link":"https:\/\/kinsta.unitedwithisrael.org\/es\/avance-israeli-contra-la-diabetes-la-primera-pildora-de-insulina-comienza-los-ensayos-finales\/","title":{"rendered":"Avance israel\u00ed contra la diabetes: La primera p\u00edldora de insulina comienza los ensayos finales"},"content":{"rendered":"

Una c\u00e1psula de insulina oral desarrollada por una empresa israel\u00ed est\u00e1 a punto de comenzar las pruebas finales, allanando el camino hacia el primer tratamiento eficaz para la diabetes sin inyecciones.<\/span><\/em><\/strong><\/p>\n

Por United with Israel<\/span><\/em><\/p>\n

Las personas que padecen diabetes requieren con frecuencia inyecciones de insulina, lo que causa dolor, molestias y cicatrices visibles que no cicatrizan. Para abordar este problema urgente de salud, una empresa con sede en Israel desarroll\u00f3 la primera c\u00e1psula de insulina oral, llamada ORMD-0801, que proporciona tratamiento para la diabetes sin necesidad de inyecciones.<\/span><\/p>\n

La p\u00edldora pas\u00f3 por varias pruebas obteniendo resultados impresionantes, coloc\u00e1ndola en la v\u00eda r\u00e1pida para la disponibilidad comercial, anunci\u00f3 Oramed la primavera pasada.<\/span><\/p>\n

Casi 500 millones de personas en todo el mundo padecen diabetes.<\/span><\/p>\n

El lunes, ORMD-0801 comenz\u00f3 las pruebas de la etapa final, marcando la casi culminaci\u00f3n de una d\u00e9cada y media de desarrollo.<\/span><\/p>\n

Si la Administraci\u00f3n de Medicamentos y Alimentos de los Estados Unidos (FDA) finalmente aprueba el desarrollo, los <\/span>diab\u00e9ticos tipo 2 podr\u00e1n comenzar a tomar pastillas de insulina<\/span><\/a> en poco m\u00e1s de tres a\u00f1os, y los diab\u00e9ticos tipo 1 podr\u00e1n usarlo despu\u00e9s de m\u00e1s pruebas.<\/span><\/p>\n

El director ejecutivo de Oramed, Nadav Kidron, dijo: \u201cCreemos que la gran eficacia demostrada al tratar a los pacientes con una dosis m\u00e1s baja demuestra a\u00fan m\u00e1s el potencial de ORMD-0801 como una soluci\u00f3n de insulina oral segura, no invasiva y eficaz para los millones de personas que sufren de diabetes en todo el mundo \u00ab.<\/span><\/p>\n

Joel M. Neutel, MD, investigador principal del ensayo de fase 2b ORMD-0801, coment\u00f3: \u201cCreo que los datos demostrados en esta segunda cohorte validan a\u00fan m\u00e1s el potencial cl\u00ednico de la insulina oral de Oramed para tener un impacto altamente beneficioso en el tratamiento de diabetes en todo el mundo \u00ab.<\/span><\/p>\n

Oramed ya desarroll\u00f3 una nueva tecnolog\u00eda de administraci\u00f3n oral de prote\u00ednas basada en m\u00e1s de 30 a\u00f1os de investigaci\u00f3n realizada por cient\u00edficos del Centro M\u00e9dico Hadassah de Jerusalem.<\/span><\/p>\n

\u00abDesde que se descubri\u00f3 la insulina, ha sido imposible administrarla por v\u00eda oral, debido a la degradaci\u00f3n y los factores que afectan la absorbancia; dado que la insulina es una prote\u00edna, el cuerpo la descompone cuando se ingiere\u00bb, inform\u00f3 <\/span>Forbes<\/span><\/em>. \u00abLa empresa utiliza un revestimiento ent\u00e9rico y una protecci\u00f3n especial que permite que la insulina permanezca intacta a trav\u00e9s del tracto gastrointestinal y llegue a la pared intestinal. A trav\u00e9s de potenciadores de absorci\u00f3n especiales, la insulina puede atravesar esta pared y llegar al h\u00edgado, donde comienza a actuar. Es importante destacar que, imita el camino natural de la insulina en el cuerpo, dirigi\u00e9ndose primero al h\u00edgado\u00bb.<\/span><\/p>\n

La creaci\u00f3n de esta c\u00e1psula de insulina no podr\u00eda haber llegado en un momento m\u00e1s oportuno, ya que el <\/span>Washington Post<\/span><\/em> inform\u00f3 el a\u00f1o pasado que el aumento de los costos de la insulina ha obligado a algunos diab\u00e9ticos a racionar su tratamiento, poniendo en riesgo sus vidas.<\/span><\/p>\n

Kidron dijo que est\u00e1 \u00abseguro de que el costo de la p\u00edldora ser\u00e1 significativamente menor que el costo de las inyecciones de insulina\u00bb, inform\u00f3 <\/span>Forbes<\/span><\/em> .<\/span><\/p>\n

Si bien una empresa india llamada Biocon tambi\u00e9n est\u00e1 trabajando en una formulaci\u00f3n de insulina oral, su producto a\u00fan no ha comenzado los ensayos avanzados de la FDA.<\/span><\/p>\n

<\/a>

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Somos un movimiento mundial que fomenta la unidad y el amor por la Tierra de Israel y el Pueblo Jud\u00edo. Todos los d\u00edas publicamos historias sobre Israel para educar, inspirar y dotar de m\u00e1s recursos a los partidarios de Israel en todo el mundo. Contribuimos a causas vitales como la construcci\u00f3n de refugios antia\u00e9reos y ayudamos a los m\u00e1s necesitados. Las donaciones de los verdaderos amigos de Israel como tu hacen que esto sea posible... as\u00ed que por favor muestra tu apoyo a Israel hoy mismo.<\/p><\/p>

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Donate to vital charities<\/strong><\/a> that help protect Israeli citizens and inspire millions around the world to support Israel too! <\/p>

Now more than ever, Israel needs your help to fight and win the war -- including on the battlefield of public opinion. <\/p>

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\"Donate<\/a><\/div><\/ad-shortcode><\/non-auwi>","protected":false},"excerpt":{"rendered":"

Una c\u00e1psula de insulina oral desarrollada por una empresa israel\u00ed est\u00e1 a punto de comenzar las pruebas finales, allanando el camino hacia el primer tratamiento eficaz para la diabetes sin inyecciones.<\/p>\n","protected":false},"author":47,"featured_media":370641,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[211],"tags":[],"class_list":["post-370639","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-luz-para-las-naciones"],"better_featured_image":{"id":370641,"alt_text":"","caption":"Diabetes. 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