{"id":366808,"date":"2020-10-19T06:04:03","date_gmt":"2020-10-19T06:04:03","guid":{"rendered":"https:\/\/kinsta.unitedwithisrael.org\/?p=366808"},"modified":"2020-10-19T09:04:03","modified_gmt":"2020-10-19T06:04:03","slug":"covid-19-cinco-pacientes-graves-curados-con-un-remedio-experimental-2","status":"publish","type":"post","link":"https:\/\/kinsta.unitedwithisrael.org\/es\/covid-19-cinco-pacientes-graves-curados-con-un-remedio-experimental-2\/","title":{"rendered":"COVID-19: cinco pacientes graves curados con un remedio experimental"},"content":{"rendered":"

Un ensayo cl\u00ednico mostr\u00f3 el potencial de Allocetra, un nuevo f\u00e1rmaco de Enlivex de Israel dise\u00f1ado a partir de c\u00e9lulas de donantes humanos sanos.<\/em><\/strong><\/p>\n

Por\u00a0Abigail Klein Leichman,<\/a> israel21c<\/p>\n

El 1 de octubre pasado el \u00faltimo de los cinco pacientes con COVID-19 en terapia intensiva que recibieron el f\u00e1rmaco experimental Allocetra fue dado de alta del Centro M\u00e9dico Universitario Hadassah en Jerusal\u00e9n.<\/p>\n

Este fue el resultado exitoso del primer ensayo cl\u00ednico mundial de Allocetra realizado por la compa\u00f1\u00eda de inmunoterapia en etapa cl\u00ednica Enlivex Therapeutics.
\nEl remedio fue creado a partir de c\u00e9lulas humanas donadas por personas sanas.<\/p>\n

Los cinco pacientes fueron dados de alta una semana despu\u00e9s de recibir Allocetra y dar negativo en las pruebas de coronavirus. Adem\u00e1s no se inform\u00f3 de efectos adversos graves relacionados con el f\u00e1rmaco a la vez que el tratamiento fue bien tolerado.<\/p>\n

El f\u00e1rmaco Allocetra fue desarrollado sobre la base de la investigaci\u00f3n del director m\u00e9dico y cient\u00edfico de Enlivex, el doctor Dror Mevorach, jefe de medicina interna y de una de las salas de coronavirus del Hadassah.<\/p>\n

En julio incluimos Enlivex como uno de los 13 prometedores tratamientos emergentes contra el COVID-19 de Israel.<\/p>\n

Este nuevo medicamento de inmunoterapia trata la disfunci\u00f3n y la insuficiencia org\u00e1nicas m\u00faltiple aguda asociada con la sepsis y el COVID-19 as\u00ed como los tumores s\u00f3lidos, al reequilibrar el sistema inmunol\u00f3gico despu\u00e9s de una tormenta de citocinas.<\/p>\n

\u201cYa hemos tratado a 15 pacientes con Allocetra en nuestro hospital, 10 con sepsis y cinco con coronavirus\u201d, afirm\u00f3 dijo el investigador principal, el doctor Vernon van Heerden, jefe de cuidados intensivos en Hadassah.<\/p>\n

El cient\u00edfico a\u00f1adi\u00f3 que \u201cbasado en los convincentes resultados preliminares que demostraron la seguridad y una indicaci\u00f3n de la eficacia de Allocetra en estos pacientes complicados, el producto de Enlivex tiene el potencial de beneficiar a los pacientes de COVID-19 en condiciones graves o cr\u00edticas\u201d.<\/p>\n

A su vez, Mevorach remarc\u00f3 que \u201ccreemos que los resultados del tratamiento con Allocetra en estos pacientes graves y cr\u00edticos con coronavirus representan una oportunidad \u00fanica para que Enlivex contribuya a los esfuerzos encaminados a combatir la pandemia mundial actual\u201d.<\/p>\n

A principios de 2020, Hadassah trat\u00f3 a 12 pacientes con COVID-19 con inmunoglobulina experimental derivada del plasma rico en anticuerpos de pacientes recuperados. El suero, preparado por la compa\u00f1\u00eda biofarmac\u00e9utica Kamada condujo a una mejora en 11 de los 12 pacientes en 24 y 48 horas, y los 11 fueron dados de alta unos d\u00edas despu\u00e9s.<\/p>\n

Sin embargo, el medicamento de Kamada est\u00e1 destinado a pacientes moderados de coronavirus mientras que Allocetra est\u00e1 pensado para casos graves o cr\u00edticos.
\nEnlivex cree que, si se aprueba Allocetra, se podr\u00eda cubrir la brecha que existe actualmente en el tratamiento de pacientes con COVID-19 en estado de gravedad.<\/p>\n

La empresa planea un ensayo cl\u00ednico de fase 2 m\u00e1s grande que se encuentra sujeto a una aprobaci\u00f3n regulatoria.\u200b<\/p>\n<\/a>

ISRAEL, PRIMER PA\u00cdS DEL MUNDO EN VACUNACI\u00d3N<\/h2>

Dona al Fondo de ayuda de United with Israel para luchar contra la grave crisis econ\u00f3mica que sufren millones de israel\u00edes <\/strong><\/a>. Israel es el pa\u00eds con un mayor \u00edndice de vacunaci\u00f3n del mundo, por poblaci\u00f3n. El 50% de los israel\u00edes ya se han vacunado.\r\nAhora es el momento de ayudar a los que m\u00e1s quieres.\r\n\r\n<\/p>

Los israel\u00edes necesitan tu ayuda. Los alimentos y suministros m\u00e9dicos pueden ser escasos. La tasa de desempleo contin\u00faa en un 25%. Comenzamos la crisis con una tasa del 4%\r\n\r\n\u00a0\u00a0<\/p>

Unidos con Israel agradece al\u00a0 Genesis Prize<\/strong><\/a> por su generoso apoyo.<\/p>

HAZ CLIC AQU\u00cd PARA HACER UNA DONACI\u00d3N<\/a><\/strong><\/p><\/cta><\/shortcode>\n

Do You Love Israel? Make a Donation - Show Your Support!<\/h2>
\"\"<\/a>

<\/p><\/div>

Donate to vital charities<\/strong><\/a> that help protect Israeli citizens and inspire millions around the world to support Israel too! <\/p>

Now more than ever, Israel needs your help to fight and win the war -- including on the battlefield of public opinion. <\/p>

Antisemitism, anti-Israel bias and boycotts are out of control. Israel's enemies are inciting terror and violence against innocent Israelis and Jews around the world. Help us fight back!<\/strong><\/a> <\/p>

STAND WTH ISRAEL - MAKE A DONATION TODAY!<\/a><\/strong><\/p><\/div><\/shortcode>

\"Donate<\/a><\/div><\/ad-shortcode><\/non-auwi>","protected":false},"excerpt":{"rendered":"

Un ensayo cl\u00ednico mostr\u00f3 el potencial de Allocetra, un nuevo f\u00e1rmaco de Enlivex de Israel dise\u00f1ado a partir de c\u00e9lulas de donantes humanos sanos.<\/p>\n","protected":false},"author":47,"featured_media":362430,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[37918],"tags":[37485,37525,37720,37854,39794],"class_list":["post-366808","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-coronavirus-en-israel","tag-coronavirus-es","tag-coronavirus-en-israel","tag-covid-19","tag-covid-19-en-israel","tag-enlivex"],"better_featured_image":{"id":362430,"alt_text":"","caption":"(Flash90\/Nati 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