{"id":311567,"date":"2019-08-22T19:49:35","date_gmt":"2019-08-22T16:49:35","guid":{"rendered":"https:\/\/kinsta.unitedwithisrael.org\/?p=311567"},"modified":"2019-08-23T09:18:27","modified_gmt":"2019-08-23T06:18:27","slug":"un-avance-israeli-podria-detener-el-cancer-cerebral","status":"publish","type":"post","link":"https:\/\/kinsta.unitedwithisrael.org\/es\/un-avance-israeli-podria-detener-el-cancer-cerebral\/","title":{"rendered":"Un avance israel\u00ed podr\u00eda detener el c\u00e1ncer cerebral"},"content":{"rendered":"

Investigadores israel\u00edes descubrieron un nuevo enfoque gen\u00e9tico que puede detener la propagaci\u00f3n del c\u00e1ncer cerebral.<\/span><\/em><\/strong><\/p>\n

Por <\/span>Israel21c.org<\/span><\/a><\/em><\/p>\n

Las met\u00e1stasis cerebrales son la consecuencia final y letal de muchos c\u00e1nceres agresivos, y los investigadores se apresuran a descubrir medidas preventivas.<\/span><\/p>\n

Un nuevo estudio de la Universidad de Tel Aviv encuentra que un ingrediente utilizado en algunas vacunas para fortalecer la respuesta inmune, puede ser un medio eficaz para prevenir met\u00e1stasis cerebrales en pacientes cuyos tumores primarios han sido extirpados.<\/span><\/p>\n

\u00abAlrededor del 20 al 40% de los pacientes con c\u00e1ncer de pulm\u00f3n, seno y melanoma desarrollan met\u00e1stasis cerebrales, y los tratamientos actuales para las met\u00e1stasis cerebrales son ineficaces\u00bb, dijo Pablo Blinder de la Facultad de Ciencias de la Vida George S. Wise de TAU.<\/span><\/p>\n

\u201cLa cirug\u00eda para extirpar tumores primarios suele ser esencial, pero el per\u00edodo inmediatamente anterior y posterior a la cirug\u00eda requiere que se suspendan todos los tratamientos de quimioterapia y radioterapia. Esto crea un alto potencial para el inicio y la r\u00e1pida progresi\u00f3n de met\u00e1stasis mortales\u201d, explic\u00f3.<\/span><\/p>\n

\u00abNuestro estudio mostr\u00f3 que una inyecci\u00f3n intravenosa de CpG-C, un adyuvante de material de ADN sint\u00e9tico, durante este per\u00edodo de tiempo espec\u00edfico reduce el desarrollo de met\u00e1stasis cerebrales\u00bb, dijo.<\/span><\/p>\n

Los cient\u00edficos probaron la eficacia de CpG-C en la reducci\u00f3n de met\u00e1stasis cerebrales en ratones, cuyos c\u00e1nceres eran de origen humano y de rat\u00f3n. Utilizaron t\u00e9cnicas de imagen de vanguardia para encontrar las c\u00e9lulas inmunes espec\u00edficas involucradas en el efecto protector.<\/span><\/p>\n

\u201cNuestro enfoque hace que las tropas inmunes est\u00e9n ‘listas para el combate’ tanto en el cerebro como en el resto del cuerpo. No es un tumor espec\u00edfico, y tiene un perfil de seguridad prometedor en humanos\u201d, agreg\u00f3 Blinder.<\/span><\/p>\n

Ser\u00e1 necesario realizar m\u00e1s pruebas en animales antes de que puedan comenzar los ensayos en humanos.<\/span><\/p>\n

\u00abEsperamos que este medicamento pueda implementarse como un tratamiento preventivo para varios tipos de tumores con met\u00e1stasis con el objetivo de prevenir o reducir las met\u00e1stasis cerebrales\u00bb, dijo Blinder.<\/span><\/p>\n

Blinder dirigi\u00f3 el estudio con Amit Benbenishty de la Escuela de Neurociencia Sagol de TAU y el Prof. Shamgar Ben-Eliyahu de la Escuela de Ciencias Psicol\u00f3gicas de TAU, en colaboraci\u00f3n con el Dr. Lior Mayo de la Escuela de Neurociencia Sagol de TAU, la Prof. Neta Erez de la Escuela de Sackler de TAU Medicina, y el Prof. Dritan Agalliu del Centro M\u00e9dico de la Universidad de Columbia. Fue publicado en <\/span>PLoS Biology<\/span><\/em> .<\/span><\/p>\n

El grupo de Ben-Eliyahu y otros han demostrado previamente que CpG-C es beneficioso para combatir tumores primarios y met\u00e1stasis en otros \u00f3rganos.<\/span><\/p>\n

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Investigadores israel\u00edes descubrieron un nuevo enfoque gen\u00e9tico que puede detener la propagaci\u00f3n del c\u00e1ncer cerebral.<\/p>\n","protected":false},"author":47,"featured_media":276089,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[211],"tags":[3655,13445,35526,896,2928,35525,15200],"class_list":["post-311567","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-luz-para-las-naciones","tag-avances-medicos","tag-avances-medicos-israel","tag-cancer-cerebral","tag-israel-es","tag-medicina-israeli","tag-tumor-cerebral","tag-universidad-de-tel-aviv"],"better_featured_image":{"id":276089,"alt_text":"brain tumor","caption":"Tumor inside brain 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