{"id":292502,"date":"2019-04-16T09:19:14","date_gmt":"2019-04-16T06:19:14","guid":{"rendered":"https:\/\/kinsta.unitedwithisrael.org\/?p=292502"},"modified":"2019-04-16T09:19:14","modified_gmt":"2019-04-16T06:19:14","slug":"presentan-una-nueva-tecnologia-israeli-para-combatir-el-cancer","status":"publish","type":"post","link":"https:\/\/kinsta.unitedwithisrael.org\/es\/presentan-una-nueva-tecnologia-israeli-para-combatir-el-cancer\/","title":{"rendered":"Presentan una nueva tecnolog\u00eda israel\u00ed para combatir el c\u00e1ncer"},"content":{"rendered":"

En los \u00faltimos a\u00f1os los cient\u00edficos descubrieron que las prote\u00ednas unidas al ARN desempe\u00f1an un papel importante en el crecimiento del c\u00e1ncer.<\/strong><\/em><\/p>\n

Estas prote\u00ednas, activas en todas las c\u00e9lulas, pero especialmente en las c\u00e9lulas cancerosas, se unen a las mol\u00e9culas de ARN y aceleran el crecimiento de los tumores. Ning\u00fan tratamiento contra el c\u00e1ncer se ha dirigido a estas prote\u00ednas. Hasta ahora.<\/p>\n

En el pr\u00f3ximo n\u00famero de Nature Communications, el profesor Rotem Karni y su equipo de la Universidad Hebrea de Jerusalem presentan una nueva tecnolog\u00eda para combatir el c\u00e1ncer. Dise\u00f1aron mol\u00e9culas se\u00f1uelo que hacen que las prote\u00ednas que se unen normalmente al ARN, se unan a ellas. Una vez unidas, estas prote\u00ednas ya no pueden unirse con las mol\u00e9culas de ARN natural en las c\u00e9lulas cancerosas y pierden su actividad promotora del c\u00e1ncer.<\/p>\n

\u201cNuestra tecnolog\u00eda es un nuevo enfoque en la guerra contra el c\u00e1ncer. Al comprender la funci\u00f3n biol\u00f3gica de las prote\u00ednas unidas al ARN, dise\u00f1amos con \u00e9xito mol\u00e9culas se\u00f1uelo que inhiben estas prote\u00ednas y nos acercan cada vez m\u00e1s a la creaci\u00f3n de un medicamento contra el c\u00e1ncer\u00bb, comparti\u00f3 Karni.<\/p>\n

Para probar los se\u00f1uelos, cuando se inyectaron en ratones sanos, las c\u00e9lulas cancerosas no se replicaron y, poco despu\u00e9s, los tumores desaparecieron.<\/p>\n

Aunque este estudio prob\u00f3 la eficacia de las mol\u00e9culas de se\u00f1uelo en las c\u00e9lulas de c\u00e1ncer de mama y cerebro, Karni explic\u00f3 que su tecnolog\u00eda permite a los cient\u00edficos adaptar los se\u00f1uelos a otros tipos de c\u00e1ncer, simplificando y mejorando el tratamiento para los pacientes. \u00abTodav\u00eda tenemos que examinar la toxicidad de las mol\u00e9culas se\u00f1uelo y probar su eficacia en animales antes de que podamos pasar a los humanos\u00bb, advirti\u00f3 Karni. \u00abSin embargo, soy optimista, dado que ya hemos logrado crear se\u00f1uelos que inhiben las prote\u00ednas de uni\u00f3n al ARN en otros tipos de c\u00e1ncer\u00bb.<\/p>\n

Hasta la fecha, Yissum, la compa\u00f1\u00eda de investigaci\u00f3n y desarrollo de la Universidad Hebrea, ha registrado una patente que describe esta tecnolog\u00eda en los Estados Unidos y Europa.<\/p>\n

Fuente: Iton Gadol<\/p>\n<\/a>

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En los \u00faltimos a\u00f1os los cient\u00edficos descubrieron que las prote\u00ednas unidas al ARN desempe\u00f1an un papel importante en el crecimiento del c\u00e1ncer.<\/p>\n","protected":false},"author":47,"featured_media":261290,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[211],"tags":[3655,12078,2928],"class_list":["post-292502","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-luz-para-las-naciones","tag-avances-medicos","tag-cancer-es","tag-medicina-israeli"],"better_featured_image":{"id":261290,"alt_text":"","caption":"(Shutterstock)","description":"","media_type":"image","media_details":{"width":1000,"height":667,"file":"2015\/11\/shutterstock_296906015.jpg","sizes":{"thumbnail":{"file":"shutterstock_296906015-150x150.jpg","width":150,"height":150,"mime-type":"image\/jpeg","ewww_image_optimizer":"Reduced by 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