{"id":173425,"date":"2016-11-17T23:24:14","date_gmt":"2016-11-17T20:24:14","guid":{"rendered":"https:\/\/kinsta.unitedwithisrael.org\/es\/?p=173425"},"modified":"2016-11-17T23:24:14","modified_gmt":"2016-11-17T20:24:14","slug":"avances-cientificos-israelies-hacen-nuevo-descubrimiento-sobre-la-enfermedad-de-alzheimer","status":"publish","type":"post","link":"https:\/\/kinsta.unitedwithisrael.org\/es\/avances-cientificos-israelies-hacen-nuevo-descubrimiento-sobre-la-enfermedad-de-alzheimer\/","title":{"rendered":"Avances. Cient\u00edficos israel\u00edes hacen nuevo descubrimiento sobre la enfermedad de Alzheimer"},"content":{"rendered":"

Los cient\u00edficos de Tel Aviv asocian el gen RGS2 con una mayor sensibilidad a la beta amiloide t\u00f3xica, desde una etapa temprana de la enfermedad. El descubrimiento no s\u00f3lo ayudar\u00eda a retrasar la progresi\u00f3n del Alzheimer, sino que tambi\u00e9n podr\u00eda proporcionar una nueva forma de detectarlo.<\/em><\/strong><\/p>\n

La enfermedad de Alzheimer sigue siendo incurable pero se han hecho grandes avances en la comprensi\u00f3n de la enfermedad. El \u00faltimo descubrimiento es que un gen, que no se hab\u00eda considerado un factor en la enfermedad de Alzheimer, tiene mucha implicancia en la enfermedad: afecta la vulnerabilidad del paciente a los efectos t\u00f3xicos de las placas amiloide-\u03b2.<\/p>\n

Espec\u00edficamente, la expresi\u00f3n reducida de RGS2 aumenta la susceptibilidad de las c\u00e9lulas nerviosas del cerebro, a los efectos perjudiciales de la placa asociada con el Alzheimer.<\/p>\n

Amiloide-\u03b2 es una prote\u00edna que es qu\u00edmicamente pegajosa por naturaleza, por lo que tiene una tendencia a agruparse. Incluso peque\u00f1os grupos pueden bloquear las se\u00f1ales entre las c\u00e9lulas nerviosas. Los grupos grandes se convierten en placa real en nuestro cerebro, que es una de las caracter\u00edsticas del Alzheimer.<\/p>\n

Te\u00f3ricamente, aumentar la expresi\u00f3n del gen RGS2 (que significa \u00abRegulador de la se\u00f1alizaci\u00f3n de prote\u00ednas 2\u00bb) podr\u00eda reducir la sensibilidad a la placa, retardando o deteniendo la progresi\u00f3n de la enfermedad neurodegenerativa cr\u00f3nica.<\/p>\n

Otra esperanza es que el descubrimiento, reportado en Translational Psychiatry, puede conducir a nuevas v\u00edas para diagnosticar el Alzheimer, por ejemplo, mediante un an\u00e1lisis de sangre.<\/p>\n

El amiloide-\u03b2 se vuelve t\u00f3xico cuando se forma una versi\u00f3n plegada err\u00f3neamente, lo que puede inducir a otras prote\u00ednas amiloides-\u03b2 a malformarse, en una especie de reacci\u00f3n en cadena. Esa primera versi\u00f3n mal plegada se llama una semilla y una vez que haya muchos de ellos, se obtiene placa amiloide.<\/p>\n

Fuente: It\u00f3n Gadol<\/p>\n<\/a>

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El descubrimiento no s\u00f3lo ayudar\u00eda a retrasar la progresi\u00f3n del Alzheimer, sino que tambi\u00e9n podr\u00eda proporcionar una nueva forma de detectarlo.<\/p>\n","protected":false},"author":47,"featured_media":139601,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[211],"tags":[25578,25579,2928],"class_list":["post-173425","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-luz-para-las-naciones","tag-alzheimer","tag-alzheimer-israel","tag-medicina-israeli"],"better_featured_image":{"id":139601,"alt_text":"Alzheimer's","caption":"(Shutterstock)","description":"","media_type":"image","media_details":{"width":1000,"height":782,"file":"2016\/02\/shutterstock_264060908.jpg","sizes":{"thumbnail":{"file":"shutterstock_264060908-150x150.jpg","width":150,"height":150,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2016\/02\/shutterstock_264060908-150x150.jpg"},"medium":{"file":"shutterstock_264060908-300x235.jpg","width":300,"height":235,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2016\/02\/shutterstock_264060908-300x235.jpg"},"medium_large":{"file":"shutterstock_264060908-768x601.jpg","width":768,"height":601,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2016\/02\/shutterstock_264060908-768x601.jpg"},"uwi-full-width":{"file":"shutterstock_264060908-665x520.jpg","width":665,"height":520,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2016\/02\/shutterstock_264060908-665x520.jpg"},"uwi-featured-carousel":{"file":"shutterstock_264060908-890x400.jpg","width":890,"height":400,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2016\/02\/shutterstock_264060908-890x400.jpg"},"uwi-featured-content":{"file":"shutterstock_264060908-290x160.jpg","width":290,"height":160,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2016\/02\/shutterstock_264060908-290x160.jpg"},"uwi-content-loop":{"file":"shutterstock_264060908-190x190.jpg","width":190,"height":190,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2016\/02\/shutterstock_264060908-190x190.jpg"},"uwi-category_list":{"file":"shutterstock_264060908-180x100.jpg","width":180,"height":100,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2016\/02\/shutterstock_264060908-180x100.jpg"},"uwi-tiny":{"file":"shutterstock_264060908-40x40.jpg","width":40,"height":40,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2016\/02\/shutterstock_264060908-40x40.jpg"},"uwi-email-featured":{"file":"shutterstock_264060908-250x170.jpg","width":250,"height":170,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2016\/02\/shutterstock_264060908-250x170.jpg"},"uwi-email":{"file":"shutterstock_264060908-200x140.jpg","width":200,"height":140,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2016\/02\/shutterstock_264060908-200x140.jpg"},"uwi-iphone":{"file":"shutterstock_264060908-960x640.jpg","width":960,"height":640,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2016\/02\/shutterstock_264060908-960x640.jpg"},"uwi-iphone-x2":{"file":"shutterstock_264060908-1000x640.jpg","width":1000,"height":640,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2016\/02\/shutterstock_264060908-1000x640.jpg"},"uwi-ipad":{"file":"shutterstock_264060908-1000x768.jpg","width":1000,"height":768,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2016\/02\/shutterstock_264060908-1000x768.jpg"},"uwi-full-width-video":{"file":"shutterstock_264060908-664x519.jpg","width":664,"height":519,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2016\/02\/shutterstock_264060908-664x519.jpg"},"uwi-fb-share-video":{"file":"shutterstock_264060908-403x315.jpg","width":403,"height":315,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2016\/02\/shutterstock_264060908-403x315.jpg"},"uwi-featured-content-video":{"file":"shutterstock_264060908-289x159.jpg","width":289,"height":159,"mime-type":"image\/jpeg","source_url":"https:\/\/kinsta.unitedwithisrael.org\/wp-content\/uploads\/2016\/02\/shutterstock_264060908-289x159.jpg"},"uwi-content-loop-video":{"file":"shutterstock_264060908-189x189.jpg","width":189,"height":189,"mime-type":"image\/jpeg","source_url":"https:\/\/kinst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