{"id":156886,"date":"2016-06-14T23:29:53","date_gmt":"2016-06-14T20:29:53","guid":{"rendered":"http:\/\/kinsta.unitedwithisrael.org\/es\/?p=156886"},"modified":"2016-06-14T23:29:53","modified_gmt":"2016-06-14T20:29:53","slug":"cientifico-de-la-universidad-bar-ilan-identifica-un-gen-que-causa-tumores-de-rinon","status":"publish","type":"post","link":"https:\/\/kinsta.unitedwithisrael.org\/es\/cientifico-de-la-universidad-bar-ilan-identifica-un-gen-que-causa-tumores-de-rinon\/","title":{"rendered":"Cient\u00edfico de la Universidad Bar- Ilan identifica un gen que causa tumores de ri\u00f1\u00f3n"},"content":{"rendered":"

Un v\u00ednculo importante entre el Gen Lin28 y el Tumor de Wilms ha sido identificado recientemente por el Dr. Achia Urbach Profesor de la Facultad de Ciencias de la Vida en Bar-Ilan. El tumor de Wilms se produce debido al desarrollo inadecuado del ri\u00f1\u00f3n durante la etapa fetal y es conocida como la forma m\u00e1s com\u00fan de c\u00e1ncer de ri\u00f1\u00f3n en ni\u00f1os.<\/em><\/strong><\/p>\n

Urbach y sus colegas encontraron que cuando un gen se sobre expresa en etapas posteriores del crecimiento fetal el desarrollo del ri\u00f1\u00f3n se atrofia. Esto hace que el tejido del ri\u00f1\u00f3n se reproduzca a una velocidad m\u00e1s r\u00e1pida de lo normal. La reproducci\u00f3n incontrolable de c\u00e9lulas fetales se traduce en crecimientos similares al tumor de Wilms.<\/p>\n

Encontraron adem\u00e1s, que al disminuir la expresi\u00f3n del gen despu\u00e9s de la r\u00e1pida replicaci\u00f3n de las c\u00e9lulas renales podr\u00edan detener el crecimiento continuo del tumor.<\/p>\n

Promover el crecimiento y la regeneraci\u00f3n renal<\/strong><\/p>\n

La unidad funcional del ri\u00f1\u00f3n, llamada la nefrona se forma exclusivamente durante el desarrollo. Si est\u00e1 da\u00f1ado por la enfermedad renal, no puede regenerarse en un adulto. La insuficiencia renal que conduce a la necesidad de di\u00e1lisis o trasplante afecta a millones de pacientes complicando en gran medida al sistema de salud.<\/p>\n

Otras manipulaciones experimentales en el Gen Lin28 podr\u00edan proporcionar una comprensi\u00f3n m\u00e1s profunda de la formaci\u00f3n de nefronas. Esto podr\u00eda permitir la restauraci\u00f3n de los n\u00fameros normales de nefronas o su regeneraci\u00f3n en los ri\u00f1ones de adultos da\u00f1ados.<\/p>\n

Fuente:\u00a0It\u00f3n Gadol<\/p>\n

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La unidad funcional del ri\u00f1\u00f3n, llamada la nefrona se forma exclusivamente durante el desarrollo. Si est\u00e1 da\u00f1ado por la enfermedad renal, no puede regenerarse en un adulto. La insuficiencia renal que conduce a la necesidad de di\u00e1lisis o trasplante afecta a millones de pacientes complicando en gran medida al sistema de salud.<\/p>\n","protected":false},"author":47,"featured_media":142166,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[211],"tags":[22563,22561,22562],"class_list":["post-156886","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-luz-para-las-naciones","tag-dr-achia-urbach","tag-tumores-de-rinon","tag-universidad-bar-ilan"],"better_featured_image":{"id":142166,"alt_text":"Israel 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